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Merck
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912220

Sigma-Aldrich

NanoFabTx PLGA-micro

for synthesis of 1-5 μm particles

同義詞:

NanoFabTx reagent kit, PLGA microparticle kit

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.23

品質等級

應用

advanced drug delivery

儲存溫度

2-8°C

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一般說明

The NanoFabTx PLGA-micro kit provides reagents (PLGA and stabilizer) and a protocol for microfluidic synthesis of microparticles between 1 to 5 μm. This reagent kit can be combined with the NanoFabTx Microfluidic - micro device kit (Cat.No. 911860) for microfluidic synthesis of PLGA micro particles.

應用

NanoFabTx PLGA-micro for synthesis of 1-5 μm particle reagent kit is designed for the synthesis of hydrophobic drug- encapsulated poly(lactic-co-glycolic acid) (PLGA) microparticles. The protocol gives users step-by-step instructions developed and tested by our formulation scientists. The protocol includes suggested conditions for incorporating drugs into the formulation and details how to tailor the parameters to yield 1 μm particles, 5 μm particles, or any size in between—all with low polydispersity. This kit affords scientists the synthetic control and reproducibility needed to encapsulate drugs, proteins, or other molecules with polymer microparticles of a chosen size and drug loading. With this kit, researchers can quickly identify the ideal microparticle size and drug loading for their research application. PLGA is a biocompatible and biodegradable polymer that has been widely used in drug delivery systems for controlled drug release of many different types of therapeutic molecules.

特點和優勢

  • Flexible synthesis tool to create uniform and reproducible nanoparticles
  • Optimized to make microparticles 1-5 μm by microfluidics with low polydispersity
  • Enables microparticle formulation screening and optimization of microparticles 1-5 μm to select ideal particle size for enhanced drug loading and controlled release
  • Based on non-toxic, biodegradable polymers

法律資訊

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

儲存類別代碼

12 - Non Combustible Liquids


分析證明 (COA)

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文章

NanoFabTx™ 平台利用即用型配方和微粒合成的微流控設備加速藥物開發。

NanoFabTx™ platform accelerates drug development with ready-to-use formulations and microfluidic devices for particle synthesis.

NanoFabTX kits enable precise drug delivery with lipid nanoparticles and liposomes for mRNA and nucleic acids.

NanoFabTX 試劑盒可利用 mRNA 和核酸的脂質奈米微粒和脂質體精確給藥。

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