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重要文件

347329

Sigma-Aldrich

(R)-(-)-3-羟基丁酸乙酯

98%

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About This Item

線性公式:
CH3CH(OH)CH2CO2C2H5
CAS號碼:
分子量::
132.16
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.22
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化驗

98%

形狀

liquid

光學活性

[α]20/D −46°, c = 1 in chloroform

光學純度

ee: 99% (GLC)

折射率

n20/D 1.42 (lit.)

bp

75-76 °C/12 mmHg (lit.)

密度

1.017 g/mL at 25 °C (lit.)

官能基

ester
hydroxyl

SMILES 字串

CCOC(=O)C[C@@H](C)O

InChI

1S/C6H12O3/c1-3-9-6(8)4-5(2)7/h5,7H,3-4H2,1-2H3/t5-/m1/s1

InChI 密鑰

OMSUIQOIVADKIM-RXMQYKEDSA-N

一般說明

(R)-3-羟基丁酸乙酯是用于制备在制药行业中所使用的生物活性化合物的一种手性结构单元。它是在聚3-羟基丁酸酯的水解过程中形成的。[1]

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

147.2 °F - closed cup

閃點(°C)

64 °C - closed cup


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A two-step enzymatic resolution process for large-scale production of (S)-and (R)-ethyl-3-hydroxybutyrate.
Fishman A, et al.
Biotechnology and Bioengineering, 74(3), 256-263 (2001)
Young-Min Han et al.
Molecular cell, 71(6), 1064-1078 (2018-09-11)
β-hydroxybutyrate (β-HB) elevation during fasting or caloric restriction is believed to induce anti-aging effects and alleviate aging-related neurodegeneration. However, whether β-HB alters the senescence pathway in vascular cells remains unknown. Here we report that β-HB promotes vascular cell quiescence, which
Xiao-Hong Chen et al.
PloS one, 9(4), e94543-e94543 (2014-04-18)
A novel carbonyl reductase (AcCR) catalyzing the asymmetric reduction of ketones to enantiopure alcohols with anti-Prelog stereoselectivity was found in Acetobacter sp. CCTCC M209061 and enriched 27.5-fold with an overall yield of 0.4% by purification. The enzyme showed a homotetrameric

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