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54965

Sigma-Aldrich

(±)-3-羟基丁酸钠

≥99.0% (NT)

同義詞:

(±)-3-羟基丁酸 钠盐

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About This Item

線性公式:
CH3CH(OH)CH2COONa
CAS號碼:
150-83-4
分子量：:
126.09
Beilstein:
4824866
EC號碼:
205-774-5
MDL號碼:
MFCD00016716
分類程式碼代碼:
12352100
PubChem物質ID:
57651496
NACRES:
NA.22
暫時無法取得訂價和供貨情況

品質等級

200

化驗

≥99.0% (NT)

mp

167-170 °C

官能基

hydroxyl

SMILES 字串

[Na+].CC(O)CC([O-])=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

InChI 密鑰

NBPUSGBJDWCHKC-UHFFFAOYSA-M

相關類別

應用

（±）-3-羟基丁酸钠已被用于研究，以了解丁酸盐对成纤维细胞生长因子 21（FGF21）的影响，其参与肝脏中的脂肪酸 β-氧化。[1]它可用于制备聚（3-羟基丁酸酯）。[2]

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
BCCL8810
BCCM2157
BCCK8667
BCCJ4209
BCCH2106

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Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Roman Tyzio et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(1), 34-45 (2011-01-07)
GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4
Novel synthesis of poly (3-hydroxybutyrate).
Juzwa M and Jedli?ski Z.
Macromolecules, 39(13), 4627-4630 (2006)
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
Nikolaj Rittig et al.
Shock (Augusta, Ga.), 44(1), 32-35 (2015-04-22)
Endotoxin administrations are used in experimental models of inflammatory disease. Short-term endotoxin tolerance in response to repeated endotoxin exposure is well known, but the duration of endotoxin tolerance in humans remains unknown. The main purpose of this study was to
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Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Is your hydroxybutyrate chemically synthesized or produced from fermentation?

    1 answer

    1. This product is produced from chemical synthesis and fermentation from cell culture. This information is presented on the lot specific Certificate of Origin. Please navigate to the ‘DOCUMENTATION’ section of the Product Detail Page to access a Certificate under the ‘Certificate of Origin’ tab:
      https://www.sigmaaldrich.com/product/aldrich/54965#product-documentation

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  4. What is the ratio of the two isomers in product 54965?

    1 answer

    1. Product 54965 is considered a racemic material, which means that there is approximately a 50/50 ratio of the two isomers. However, it is not tested or characterized, so it cannot be guaranteed to be exactly 50/50, but it should be close.

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