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196282

Sigma-Aldrich

3-噻吩甲醛

98%

同義詞:

3-噻吩甲醛, 3-噻吩醛, 3-甲醛噻吩, 噻吩-3-甲醛, 硫呋喃-3-甲醛

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About This Item

經驗公式(希爾表示法):
C5H4OS
CAS號碼:
分子量::
112.15
Beilstein:
105889
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
暫時無法取得訂價和供貨情況

蒸汽壓力

0.31 mmHg ( 20 °C)

化驗

98%

形狀

liquid

自燃溫度

>392 °F

折射率

n20/D 1.583 (lit.)

bp

194-196 °C (lit.)
86-87 °C/20 mmHg (lit.)

密度

1.28 g/mL at 25 °C (lit.)

官能基

aldehyde

儲存溫度

2-8°C

SMILES 字串

[H]C(=O)c1ccsc1

InChI

1S/C5H4OS/c6-3-5-1-2-7-4-5/h1-4H

InChI 密鑰

RBIGKSZIQCTIJF-UHFFFAOYSA-N

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應用

3-噻吩甲醛已用于合成:
  • 一系列 4-取代 2-噻吩磺酰胺[1]
  • 4′-去甲基表鬼臼毒素-β-D-葡萄糖苷和表鬼臼毒素-β-D-葡萄糖苷的缩醛和缩酮衍生物[2]
  • 1,2-二-3-噻吩基-2-羟基乙酮(3,3′-荆芥),安息香的 3-噻吩基对称类似物[3]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

167.0 °F - closed cup

閃點(°C)

75 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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J M Holmes et al.
Journal of medicinal chemistry, 37(11), 1646-1651 (1994-05-27)
A series of 4-substituted 2-thiophenesulfonamides was prepared from 3-thiophenecarboxaldehyde using metalation chemistry developed for 3-furaldehyde. Several of these compounds inhibit carbonic anhydrase II in vitro at concentrations of less than 10 nM. In addition, none of these compounds exhibit sensitization
R S Gupta et al.
Anti-cancer drug design, 2(1), 1-12 (1987-08-01)
We have synthesized acetal and ketal derivatives of 4'-demethylepipodophyllotoxin-beta-D-glucoside (DMEPG) and epipodophyllotoxin-beta-D-glucoside (EPG) with a number of different aldehydes (viz. acetaldehyde, propionaldehyde, 2-thiophenecarboxaldehyde, 3-thiophenecarboxaldehyde, 2-furancarboxaldehyde, benzaldehyde, phenylacetaldehyde, hydrocinnamaldehyde) and acetone. The cross resistance of these compounds towards a set of
1, 2-Di-3-thienyl-2-hydroxyethanone (3, 3′-thenoin).
Crundwell G, et al.
Acta Crystallographica Section E, Structure Reports Online, 58(6), o668-o670 (2002)
Kollur Shiva Prasad et al.
Molecules (Basel, Switzerland), 25(12) (2020-06-26)
Herein we report the synthesis and structural elucidation of two novel imine-based ligands, 2-(1,10-phenanthrolin-5-yl)imino)methyl)-5-bromophenol (PIB) and N-(1,10-phenanthrolin-5-yl)-1-(thiophen-3-yl)methanimine (PTM) ligands. An in vitro cytotoxicity assay of the synthesized molecules was carried out against breast, cervical, colorectal, and prostate cancer cell lines
Kyungsil Yoon et al.
Cells, 8(3) (2019-03-15)
Chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is an orphan receptor and member of the nuclear receptor superfamily. Among a series of methylene substituted diindolylmethanes (C-DIMs) containing substituted phenyl and heteroaromatic groups, we identified 1,1-bis(3'-indolyl)-1-(4-pyridyl)-methane (DIM-C-Pyr-4) as an activator of

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