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重要文件

B57001

Sigma-Aldrich

2-溴苯甲醛

98%

同義詞:

2-甲酰溴苯

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About This Item

線性公式:
BrC6H4CHO
CAS號碼:
分子量::
185.02
Beilstein:
636132
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

98%

形狀

liquid

折射率

n20/D 1.595 (lit.)

bp

230 °C (lit.)

mp

16-19 °C (lit.)

密度

1.585 g/mL at 25 °C (lit.)

SMILES 字串

Brc1ccccc1C=O

InChI

1S/C7H5BrO/c8-7-4-2-1-3-6(7)5-9/h1-5H

InChI 密鑰

NDOPHXWIAZIXPR-UHFFFAOYSA-N

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一般說明

2-溴苯甲醛是是一种多功能合成砌块,用于Suzuki-Miyaura 和Buchwald-Hartwig 反应、交叉偶联反应,以形成碳-碳和碳-杂原子键。[1]

應用

2-溴苯甲醛的合成应用 包括:
  • 通过铜催化的级联反应合成氮杂稠合多环喹啉。[2]
  • CuI 催化偶联N-芳基肼合成1-取代吲唑。[3]
  • 它是抗癌药物 (-)-紫杉醇全合成中的关键起始原料。[4]
  • 钯/铜催化的 2-溴苯甲醛和不饱和亚胺衍生的末端乙炔的偶联和环化反应可用于合成广泛的异喹啉,包括十苯胺B。[5]
  • 芴-9-酮可在钯 (0) 催化剂存在下,由 2-(三甲基硅烷基)芳基三氟甲磺酸酯与 2-溴苯甲醛原位生成炔环合成。[6]
  • 它也可用于构建多种甾体骨架,其中环 A 来源于 2-溴苯甲醛。[7]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

203.0 °F - closed cup

閃點(°C)

95 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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