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Merck
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文件

167398

Sigma-Aldrich

氨基甲酸叔丁酯

98%

同義詞:

Boc-胺

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About This Item

線性公式:
NH2COOC(CH3)3
CAS號碼:
分子量::
117.15
Beilstein:
1744500
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

solid

mp

105-108 °C (lit.)

SMILES 字串

CC(C)(C)OC(N)=O

InChI

1S/C5H11NO2/c1-5(2,3)8-4(6)7/h1-3H3,(H2,6,7)

InChI 密鑰

LFKDJXLFVYVEFG-UHFFFAOYSA-N

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一般說明

氨基甲酸 丁酯与各种芳基(Het)卤化物的钯催化交叉偶联反应已被研究,其中Cs2CO3 作为1,4-二恶烷(溶剂)中的碱

應用

氨基甲酸叔丁酯被用于 N-Boc保护的苯胺钯催化合成。它被用于合成四取代吡咯,在C-3位以酯或酮基官能化

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Maximilian Tromayer et al.
Polymer chemistry, 8(2), 451-460 (2017-03-07)
The possibility of the direct encapsulation of living cells
One-Pot Three-Component Synthesis of Tetrasubstituted NH Pyrroles from Secondary Propargylic Alcohols, 1, 3-Dicarbonyl Compounds and tert-Butyl Carbamate.
Cadierno V, et al.
Journal of Heterocyclic Chemistry, 47(1), 233-236 (2010)
Swapna Bhagwanth et al.
The Journal of organic chemistry, 74(12), 4634-4637 (2009-06-13)
The scope of Pd-catalyzed synthesis of N-Boc-protected anilines from aryl bromides and commercially available tert-butyl carbamate is described. For the first time, this process can be conducted at room temperature (17-22 degrees C) using a combination of Pd(2)dba(3).CHCl(3) and a
Pd-catalyzed amidation of aryl (Het) halides with< i> tert</i>-butyl carbamate.
Qin L, et al.
Tetrahedron Letters, 51(33), 4446-4448 (2010)
Zeljko M Svedružić et al.
PloS one, 7(3), e32293-e32293 (2012-04-06)
We describe molecular processes that can facilitate pathogenesis of Alzheimer's disease (AD) by analyzing the catalytic cycle of a membrane-imbedded protease γ-secretase, from the initial interaction with its C99 substrate to the final release of toxic Aβ peptides. The C-terminal

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