跳轉至內容
Merck

KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1

同義詞:
KIR1.1, ROMK, ROMK1
物種:
UniProtKB ID:
基因 ID:
  • Human(3758) Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56379) potassium inwardly-rectifying channel, subfamily J, member 1
  • Rat(24521) potassium inwardly-rectifying channel, subfamily J, member 1
  • chicken(428236) potassium inwardly-rectifying channel, subfamily J, member 1
  • Horse(100072580) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic cat(101091140) potassium inwardly-rectifying channel, subfamily J, member 1
  • cow(539250) potassium inwardly-rectifying channel, subfamily J, member 1
  • dog(489285) potassium inwardly-rectifying channel, subfamily J, member 1
  • naked mole-rat(101720253) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic guinea pig(100722828) potassium inwardly-rectifying channel, subfamily J, member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Activator

產品編號
描述
物種
二氮嗪, ,
物種
rat, mouse, human

Small Molecule - Antagonist

產品編號
描述
物種
Cromakalim, ,
物種
rat
格列本脲, meets USP testing specifications,
物種
rat, human
格列本脲, ≥99% (HPLC),
物種
rat, human
氯磺丙脲, analytical standard, ≥97%,
物種
human, mouse
甲苯磺丁脲, analytical standard,
物種
human, mouse

Antibodies

產品編號
描述
物種活性
應用
Anti-KCNJ1 antibody produced in rabbit, affinity isolated antibody,
物種活性
dog, guinea pig, horse, human, rabbit, rat
應用
western blot
Anti-ROMK antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
Anti-KCNJ1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
western blot

Small Molecule - Blocker

產品編號
描述
物種
格列齐特, powder, ≥98%,
物種
human
格列美脲, ≥98% (HPLC), solid,
物種
human
瑞格列奈, ≥98% (HPLC), solid,
物種
human
格列吡嗪, solid,
物種
human
格列本脲, meets USP testing specifications,
物種
rat, human

Small Molecule - Inhibitor

產品編號
描述
物種
利诺吡啶, ≥98% (HPLC),
物種
rat
VU591, ≥98% (HPLC),
物種
human
Tertiapin-Q trifluoroacetate salt, ≥97% (HPLC),
物種
rat, human, mouse
氯磺丙脲, analytical standard, ≥97%,
物種
human, mouse
甲苯磺丁脲, analytical standard,
物種
human, mouse

Small Molecule - Ligand

產品編號
描述
物種
格列美脲, ≥98% (HPLC), solid,
物種
human
格列吡嗪, solid,
物種
human
格列本脲, ≥99% (HPLC),
物種
rat, human
氯磺丙脲, analytical standard, ≥97%,
物種
human, mouse

Small Molecule - Opener

產品編號
描述
物種
米诺地尔, ≥99% (TLC),
物種
human
二氮嗪, ,
物種
rat, mouse, human