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文件

T0891

Supelco

甲苯磺丁脲

analytical standard

同義詞:

1-丁基-3-（4-甲基苯磺酰基）脲, N-[(丁基氨基)羰基]-4-甲基苯磺酰胺

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About This Item

經驗公式（希爾表示法）:
C12H18N2O3S
CAS號碼:
64-77-7
分子量：:
270.35
Beilstein:
1984428
EC號碼:
200-594-3
MDL號碼:
MFCD00027169
分類程式碼代碼:
41116107
PubChem物質ID:
329826629
NACRES:
NA.24

生物源

synthetic (organic)

品質等級

200

等級

analytical standard

化驗

97.0-103.0%

技術

HPLC: suitable
gas chromatography (GC): suitable

溶解度

ethanol: 50 mg/mL, clear, colorless

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES 字串

CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)

InChI 密鑰

JLRGJRBPOGGCBT-UHFFFAOYSA-N

基因資訊

human ... ABCC8(6833) , ALB(213) , CYP1A2(1544) , CYP2C9(1559) , EPHX2(2053) , KCNJ1(3758) , KCNJ11(3767)
mouse ... Ephx2(13850)

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相關類別

應用

有关合适仪器技术的更多信息，请参考产品′s分析证书。如需进一步支持，请联系技术服务。

生化／生理作用

抗糖尿病制剂。由CYP2C9（甲苯磺丁脲羟化酶）所代谢。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析證明 (COA)

Lot/Batch Number
0000355922
0000358284
0000305112
0000305113
0000330715

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Kevin S C Hamming et al.
Diabetes, 59(7), 1686-1693 (2010-04-24)
The sodium-calcium exchanger isoform 1 (NCX1) regulates cytoplasmic calcium (Ca(2+)(c)) required for insulin secretion in beta-cells. NCX1 is alternatively spliced, resulting in the expression of splice variants in different tissues such as NCX1.3 and -1.7 in beta-cells. As pharmacological inhibitors
Ioannis Eleftherianos et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(29), 12024-12029 (2011-07-02)
The effects of the cellular environment on innate immunity remain poorly characterized. Here, we show that in Drosophila ATP-sensitive potassium channels (K(ATP)) mediate resistance to a cardiotropic RNA virus, Flock House virus (FHV). FHV viral load in the heart rapidly
Jean-Claude Henquin et al.
Diabetes, 62(5), 1689-1696 (2013-01-01)
Congenital hyperinsulinism causes persistent hypoglycemia in neonates and infants. Most often, uncontrolled insulin secretion (IS) results from a lack of functional K(ATP) channels in all β-cells or only in β-cells within a resectable focal lesion. In more rare cases, without
Ruurdtje Hoekstra et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(3), 562-567 (2012-12-15)
The human liver cell line HepaRG has been recognized as a promising source for in vitro testing of metabolism and toxicity of compounds. However, currently the hepatic differentiation of these cells relies on exposure to dimethylsulfoxide (DMSO), which, as a
Arian F Baquero et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(30), 9982-9994 (2014-07-25)
Leptin is well known for its role in the regulation of energy homeostasis in adults, a mechanism that at least partially results from the inhibition of the activity of NPY/AgRP/GABA neurons (NAG) in the arcuate nucleus of the hypothalamus (ARH).
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