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Anti-RIP3 antibody produced in rabbit

Name: Anti-RIP3 antibody produced in rabbit
Brand: SIGMA

affinity isolated antibody

Synonym(s):

Anti-Receptor-Interacting serine-threonine kinase 3

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03097232

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

Pricing and availability is not currently available.

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

mol wt

predicted mol wt 57 kDa

species reactivity

rat, human, mouse

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

Q9QZL0

shipped in

dry ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

mouse ... Ripk3(56532)

Description

Immunogen

a peptide corresponding to amino acids 473-486 of murine RIP3.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP2283.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	WH0008767M1	WH0054101M1	HPA015257
Sigma-Aldrich PRS2283 Anti-RIP3 antibody produced in rabbit	Sigma-Aldrich WH0008767M1 Monoclonal Anti-RIPK2 antibody produced in mouse	Sigma-Aldrich WH0054101M1 Monoclonal Anti-RIPK4 antibody produced in mouse	Sigma-Aldrich HPA015257 Anti-RIPK1 antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level -	Quality Level 100
biological source rabbit	biological source mouse	biological source mouse	biological source rabbit
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
mol wt predicted mol wt 57 kDa	mol wt -	mol wt -	mol wt -
Gene Information mouse ... Ripk3(56532)	Gene Information human ... RIPK2(8767)	Gene Information human ... RIPK4(54101)	Gene Information human ... RIPK1(8737)

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

22830004

22830704

2283-0704

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Retinal phototoxicity and the evaluation of the blue light hazard of a new solid-state lighting technology.

Imene Jaadane et al.

Scientific reports, 10(1), 6733-6733 (2020-04-23)

Exposure Limit Values (ELV) for artificial lighting were defined in order to prevent light-induced damage to the retina. The evaluation of the lighting devices include the correction of their spectra by the B(λ) function or blue light hazard function, representing

The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis.

Xia-Lian Wu et al.

Nature communications, 12(1), 1627-1627 (2021-03-14)

RIPK3 amyloid complex plays crucial roles during TNF-induced necroptosis and in response to immune defense in both human and mouse. Here, we have structurally characterized mouse RIPK3 homogeneous self-assembly using solid-state NMR, revealing a well-ordered N-shaped amyloid core structure featured

Mixed lineage kinase domain-like protein induces RGC-5 necroptosis following elevated hydrostatic pressure.

Lvshuang Liao et al.

Acta biochimica et biophysica Sinica, 49(10), 879-889 (2017-10-06)

Receptor-interacting protein 3 (RIP3) is an essential component of the necroptosis signaling pathway. Phosphorylation of its downstream target, mixed lineage kinase domain-like protein (MLKL), has been proposed to induce necroptosis by initiating Ca2+ influx. Our previous studies have shown that

Key Documents

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Anti-RIP3 antibody produced in rabbit

affinity isolated antibody

Select a Size

About This Item

biological source

Quality Level

conjugate

antibody form

antibody product type

clone

mol wt

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

Immunogen

Application

Physical form

Other Notes

Disclaimer

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Storage Class

flash_point_f

flash_point_c

Documentation

Certificates of Analysis (COA)

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