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5 G
$71.50
25 G
$193.00
About This Item
经验公式（希尔记法）:
C35H53NO3
CAS号:
分子量:
535.80
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.79
推荐产品
方案
≥98%
表单
solid or liquid
颜色
white to yellow
储存温度
2-8°C
SMILES字符串
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)c3cccnc3)c(C)c(C)c2O1
InChI
1S/C35H53NO3/c1-24(2)13-9-14-25(3)15-10-16-26(4)17-11-20-35(8)21-19-31-29(7)32(27(5)28(6)33(31)39-35)38-34(37)30-18-12-22-36-23-30/h12,18,22-26H,9-11,13-17,19-21H2,1-8H3/t25-,26-,35-/m1/s1
InChI key
MSCCTZZBYHQMQJ-AZAGJHQNSA-N
一般描述
α-Tocopherol nicotinate is a fat soluble vitamin.[1] It is an ester of tocopherol and niacin. Niacin is linked to the hydroxyl group of active vitamin E in this ester.[2] α-Tocopherol is a form of vitamin E,[3] which is available through dietary sources.[4] RRR-α-tocopherol is a natural form of α-Tocopherol.[5]
应用
(±)-α-Tocopherol nicotinate has been used in metabolic studies to assess its biological functions in rats.[2]
生化/生理作用
α-Tocopherol is a radical-chain breaker owing to its anti-oxidant property.[6]
Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. α-Tocopherol nicotinate is used along the α-Tocopherol acetate, α-Tocopherol succinate and other esterified forms as a vitamin E supplement with similar but differential activities.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
其他客户在看
N Inagaki et al.
Journal of pharmacobio-dynamics, 7(1), 70-74 (1984-01-01)
Effect of vitamin E (alpha-tocopheryl acetate and alpha-tocopheryl nicotinate) on IgE antibody formation in mice was investgiated . Female BALB/c mice were immunized with dinitrophenylated ascaris protein (DNP-As) and aluminium hydroxide gel (alum). Supplementation of vitamin E in diets or
A Funakoshi et al.
The Tohoku journal of experimental medicine, 148(4), 393-401 (1986-04-01)
The fasting serum levels of alpha-tocopherol were determined by high-pressure liquid chromatography in 13 patients with chronic pancreatitis of whom 7 were positive for pancreatic calcification (CCP) and 6, negative (NCP) and 10 healthy subjects. The fasting serum levels of
K N Prasad et al.
Cancer research, 42(2), 550-555 (1982-02-01)
The effects of various forms of tocopherol (vitamin E) on the growth and differentiation of mouse melanoma (B-16) and mouse fibroblast (L-cells) cells in culture were studied. D-alpha-tocopherol acid succinate induced morphological alterations and growth inhibition in melanoma cells. When
[Effects of soysterol, pantethine and dl-alpha-tocopheryl nicotinate on hyperlipemia in rats (author's transl)].
S Nakayama et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 78(3), 191-202 (1981-09-01)
Mitsuru Nakazawa et al.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 225(2), 120-126 (2010-10-16)
To assess the effects of nilvadipine on the progression of central visual field defect in retinitis pigmentosa (RP). Prospective, randomized, nonmasked, single-center trial. Patients with RP were randomly divided into a treated group receiving oral nilvadipine at 4 mg/day for
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