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Merck

M1537

Sigma-Aldrich

微囊藻素 RR 来源于藻类

≥90% (HPLC), solid

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About This Item

经验公式(希尔记法):
C49H75N13O12
分子量:
1038.20
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77

生物来源

microbial (Microcystis aerguinosa)

质量水平

方案

≥90% (HPLC)

表单

solid

分子量

~_1.0 kDa

颜色

white

溶解性

ethanol: water (1:1): 0.50 mg/mL

储存温度

−20°C

SMILES字符串

COC(Cc1ccccc1)C(C)\C=C(C)\C=C\C2NC(=O)C(CCCNC(N)=N)NC(=O)C(C)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(C)NC(=O)C(=C)N(C)C(=O)CCC(NC(=O)C2C)C(O)=O)C(O)=O

InChI

1S/C49H75N13O12/c1-26(24-27(2)37(74-8)25-32-14-10-9-11-15-32)18-19-33-28(3)40(64)60-36(46(70)71)20-21-38(63)62(7)31(6)43(67)56-30(5)42(66)59-35(17-13-23-55-49(52)53)45(69)61-39(47(72)73)29(4)41(65)58-34(44(68)57-33)16-12-22-54-48(50)51/h9-11,14-15,18-19,24,27-30,33-37,39H,6,12-13,16-17,20-23,25H2,1-5,7-8H3,(H,56,67)(H,57,68)(H,58,65)(H,59,66)(H,60,64)(H,61,69)(H,70,71)(H,72,73)(H4,50,51,54)(H4,52,53,55)/b19-18+,26-24+/t27-,28-,29-,30+,33-,34-,35-,36+,37-,39+/m0/s1

InChI key

JIGDOBKZMULDHS-UUHBQKJESA-N

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生化/生理作用

Inhibitor of protein phosphatase 2A with lower toxicity than microcystin LR.
Treatment of tilapia fish with microcystin RR caused an increase in acid and alkaline phosphatases and resulted in significant renal and liver damage.

象形图

Skull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Loyda Atencio et al.
Toxicologic pathology, 36(3), 449-458 (2008-04-29)
Microcystins (MC) are frequently present in cyanobacterial blooms in rivers and lakes, increasing the risk of toxicity to both animals and humans. There more than eighty reported microcystins, and the present study was undertaken to determine whether MC-LR and MC-RR
M Sathishkumar et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 45(14), 1877-1884 (2010-10-19)
Microcystins (cyclic heptapeptides), produced by a number of freshwater cyanobacteria, are of health concern in potable water supplies. In this article, the adsorptive removal of microcystin-RR (MCRR) from the aqueous solution by a low-cost adsorbent, peat, was investigated. The BET
Fares A Al Momani et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 45(6), 719-731 (2010-04-15)
A rapid scan-stopped flow (RS-SF) reactor was used to study reaction between ozone and cyanobacterial toxins [microcystin-LR (MC-LR) and microcystin-RR (MC-RR)] at different pH values and over a temperature range of 20-30 degrees C. The ozonation reaction was very effective
Hai Yan et al.
Chemosphere, 87(1), 12-18 (2011-12-20)
Enzymes encoded by genes biodegrading microcystins (MCs) can help reveal the function of genes and biodegradation pathway of MCs. Here the first and important gene (USTB-05-A, 1,008 bp) involved in biodegradation of microcystin-RR (MC-RR) was cloned from Sphingopyxis sp. USTB-05
Nanqin Gan et al.
Environmental microbiology, 14(3), 730-742 (2011-11-02)
Microcystis is a cosmopolitan genus of cyanobacteria and occurs in many different forms. Large surface blooms of the cyanobacterium are well known in eutrophic lakes throughout the globe. We evaluated the role of microcystins (MCs) in promoting and maintaining bloom-forming

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