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Merck
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主要文件

L8039

Sigma-Aldrich

脂蛋白,高密度 来源于人类血浆

≥95% (SDS-PAGE), solution

别名:

α-脂蛋白, HDL, 高密度脂蛋白

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10 MG
$886.00

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10 MG
$886.00

About This Item

MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25

$886.00


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生物来源

human plasma

质量水平

方案

≥95% (SDS-PAGE)

表单

solution

包装

vial of 10 mg protein

技术

cell culture | mammalian: suitable

UniProt登记号

官能团

ester
phospholipid

运输

wet ice

储存温度

2-8°C

基因信息

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生化/生理作用

高密度脂蛋白(HDL)是胆固醇从血液、组织和器官转运到肝脏的转运剂,在肝脏中胆固醇会分解。 这个过程最终有助于清除动脉胆固醇。HDL俗称“好胆固醇”,占人体总胆固醇的20%-30%。

HDL用于心血管研究和开发潜在的心血管风险管理方法。

外形

含150 mM NaCl和0.01% EDTA的溶液,pH 7.4

其他说明

免责声明

仅供研究使用。本品在法国的科研应用受到监管,包括用于进口和出口活动(法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2)。如《公共卫生法典》所述,购买者(即最终用户)需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


历史批次信息供参考:

分析证书(COA)

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Mark J Cziraky et al.
Journal of managed care pharmacy : JMCP, 14(8 Suppl), S3-28 (2009-11-07)
Most clinicians recognize the importance of reducing low-density lipoprotein cholesterol (LDL-C) and, therefore, address this therapeutic need to decrease cardiovascular disease risk. In addition to the critical role that LDL-C plays, recent studies have shown the contribution of other lipid
Kyung-Hyun Cho
Medicines (Basel, Switzerland), 8(7) (2021-08-07)
The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I
Santiago Redondo et al.
Lipids in health and disease, 10, 175-175 (2011-10-12)
Epidemiologic studies indicate a strong inverse correlation between plasma levels of high-density lipoproteins (HDL) and cardiovascular disease (CVD). The most relevant cardioprotective mechanism mediated by HDL is thought to be reverse cholesterol transport (RCT). New insights in HDL biology and
Tisha R Joy
Pharmacology & therapeutics, 135(1), 18-30 (2012-04-03)
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has been associated with a 25-30% reduction in cardiovascular disease risk. However, there still remains a significant and quantifiable risk. Since epidemiologic data have demonstrated that low levels of high-density lipoprotein cholesterol (HDL-C)
Joseph B Dubé et al.
Current opinion in lipidology, 23(2), 133-140 (2012-02-14)
Lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular disease; we highlight the most recent research initiatives that have sought to define Lp(a)-dependent pathogenicity as well as pharmacologic approaches to lowering Lp(a). Recent large-scale meta-analyses have confirmed elevated Lp(a) concentrations to

商品

由于胆固醇是水不溶性分子,必须包装后才能在血浆中运输。包装胆固醇、胆固醇酯和甘油三酯以便运输的颗粒称为脂蛋白。

Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.

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