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Merck

D4162

Sigma-Aldrich

4,4'-二苯胺基-1,1'-联萘-5,5'-二磺酸 二钾盐

fluorescent probe

别名:

Bis-ANS

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About This Item

经验公式(希尔记法):
C32H22K2N2O6S2
CAS号:
分子量:
672.85
Beilstein:
5714637
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

化驗

≥97% (HPLC)

形狀

powder

溶解度

methanol with 1 M NH4OH: 5 mg/mL, clear

SMILES 字串

[K+].[K+].[O-]S(=O)(=O)c1cccc2c(ccc(Nc3ccccc3)c12)-c4ccc(Nc5ccccc5)c6c(cccc46)S([O-])(=O)=O

InChI

1S/C32H24N2O6S2.2K/c35-41(36,37)29-15-7-13-25-23(17-19-27(31(25)29)33-21-9-3-1-4-10-21)24-18-20-28(34-22-11-5-2-6-12-22)32-26(24)14-8-16-30(32)42(38,39)40;;/h1-20,33-34H,(H,35,36,37)(H,38,39,40);;/q;2*+1/p-2

InChI 密鑰

VWLWTJHKQHRTNC-UHFFFAOYSA-L

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應用

蛋白质的双功能荧光探针。

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Sandip Kumar Nandi et al.
Journal of inorganic biochemistry, 188, 62-75 (2018-08-20)
Mycobacterium leprae uptakes various bivalent metal ions via different transporters in host species. Uptake of Cu2+ and Zn2+ are essential for generation of superoxide dismutases and catalases, which provide defense against reactive oxygen species mediated death of this pathogen in
A R Prasad et al.
Biochemistry, 25(3), 739-742 (1986-02-11)
The fluorescent apolar probe bis(8-anilinonaphthalene-1-sulfonate) (Bis-ANS) has been used to detect structural correlates of the well-known but poorly understood decay of tubulin function, by which tubulin loses its ability to polymerize and bind drugs in a complex, time-dependent way. The
Cooperative effects in binding by bovine serum albumin. I. The binding of 1-anilino-8-naphthalenesulfonate. Fluorimetric titrations.
E Daniel et al.
Biochemistry, 5(6), 1893-1900 (1966-06-01)
Jamie R Johnston et al.
The Journal of biological chemistry, 294(52), 20054-20069 (2019-11-22)
Aberrant regulation of myocardial force production represents an early biomechanical defect associated with sarcomeric cardiomyopathies, but the molecular mechanisms remain poorly defined. Here, we evaluated the pathogenicity of a previously unreported sarcomeric gene variant identified in a pediatric patient with
Zsolt Datki et al.
Acta neuropathologica communications, 6(1), 6-6 (2018-01-31)
Neurodegenerative diseases are linked to a systemic enzyme resistance of toxic aggregated molecules and their pathological consequences. This paper presents a unique phenomenon that Philodina acuticornis, a bdelloid rotifer, is able to catabolize different types of neurotoxic peptide and protein

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