跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

D1413

Sigma-Aldrich

2′,3′-二脱氢-3′-脱氧胸苷

≥98% (TLC)

别名:

Stavudine

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C10H12N2O4
CAS号:
3056-17-5
分子量:
224.21
MDL编号:
MFCD00132921
UNSPSC代码:
12352200
PubChem化学物质编号:
24278356
NACRES:
NA.77
价格与库存信息目前不能提供

质量水平

200

方案

≥98% (TLC)

表单

powder

储存温度

−20°C

SMILES字符串

CC1=CN([C@@H]2O[C@H](CO)C=C2)C(=O)NC1=O

InChI

1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1

InChI key

XNKLLVCARDGLGL-JGVFFNPUSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

2′,3′-Didehydro-3′-deoxythymidine (d4T), a pyrimidine analogue is the inhibitor of reverse transcriptase.[1]

应用

2′,3′-Didehydro-3′-deoxythymidine has been used in cell treatment.[2] It has also been used as a drug in Caenorhabditis elegans to study drug induced mitochondrial toxicity.[3] It has also been used in the preclinical evaluation of GS-9160.[4]

生化/生理作用

2′,3′-Didehydro-3′-deoxythymidine is a nucleoside analog, which inhibits HIV replication in vitro. Stavudine has the ability to enter the cells by non-facilitated diffusion. It possesses inhibitory activity against moloney murine leukemia virus, friend murine leukemia virus and simian immunodeficiency virus.[5]

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000382188
0000320030
0000382188
0000301501
0000301501

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 2

1 of 2

胸苷 ≥99%

Sigma-Aldrich

T9250

胸苷

细胞色素 C 来源于马心脏 ≥95% (SDS-PAGE)

Sigma-Aldrich

C2506

细胞色素 C 来源于马心脏

Nittaya Phanuphak et al.
Antiviral therapy, 17(8), 1521-1531 (2012-12-12)
Due to superior long-term toxicity profiles, zidovudine (AZT) and tenofovir disoproxil fumarate (TDF) are preferred over stavudine (d4T) for first-line antiretroviral regimens. However, short-term d4T use could be beneficial in avoiding AZT-induced anaemia. We randomized (1:1:1) 150 treatment-naive Thai HIV-infected
Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase
Jones G S, et al.
Antimicrobial Agents and Chemotherapy, 53(3), 1194-1203 (2009)
Caenorhabditis elegans as a model system for studying drug induced mitochondrial toxicity
de Boer R, et al.
PLoS ONE, 10(5), e0126220-e0126220 (2015)
2?, 3?-didehydro-3?-deoxythymidine (d4T) in patients with AIDS or AIDS-related complex: a phase I trial
Browne M J, et al.
The Journal of Infectious Diseases, 167(1), 21-29 (1993)
Stephanie Shiau et al.
The Journal of pediatrics, 162(6), 1138-1145 (2013-01-15)
To describe the effects of age at antiretroviral therapy (ART) initiation on growth outcomes among children infected with HIV followed for 48 months after treatment initiation. This secondary analysis describes anthropometric changes in children infected with HIV in Johannesburg, South
查看所有相关文献

Questions

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门