所有图片(2)
选择尺寸
变更视图
10 MG
$125.00
25 MG
$311.00
About This Item
线性分子式:
(C21H27NO2)2 · C4H6O6
CAS号:
分子量:
800.98
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
储存温度
room temp
质量水平
SMILES字符串
OC(C(O)C(O)=O)C(O)=O.CC(C(O)c1ccc(O)cc1)N2CCC(CC2)Cc3ccccc3.CC(C(O)c4ccc(O)cc4)N5CCC(CC5)Cc6ccccc6
InChI
1S/2C21H27NO2.C4H6O6/c2*1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17;5-1(3(7)8)2(6)4(9)10/h2*2-10,16,18,21,23-24H,11-15H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)
InChI key
DMPRDSPPYMZQBT-UHFFFAOYSA-N
基因信息
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
一般描述
生化/生理作用
作用于多胺站点的 NMDA 拮抗剂；神经保护剂；α-肾上腺素能中枢和外周血管扩张剂；α 2 肾上腺素能受体配体。
特点和优势
该化合物是受体分类及信号转导手册上谷氨酸受体（离子通道家族）页面上的特色化合物。想要浏览手册的其他页面， 请单击此处。
这种化合物是神经科学研究的特色产品。点击此处发现更多特色神经科学产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Kenneth R Tovar et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(23), 8065-8073 (2012-06-08)
The amino-terminal domains of NMDA receptor subunits are important for receptor assembly and desensitization, and incorporate the high-affinity binding sites for zinc and ifenprodil. These amino-terminal ligands are thought of as subunit-specific receptor inhibitors. However, multiple NMDA receptor subtypes contribute
Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil
Kobayashi T, et al.
Neuropsychopharmacology, 31(3), 516-516 (2006)
Involvement of NMDA receptor subtypes in cortical spreading depression in rats assessed by fMRI
Shatillo A, et al.
Neuropharmacology, 93, 164-170 (2015)
NMDA receptor antagonists attenuate intrathecal morphine-induced pruritus through ERK phosphorylation
Shen L, et al.
Molecular Brain, 11(1), 35-35 (2018)
Austen J Milnerwood et al.
Neurobiology of disease, 48(1), 40-51 (2012-06-07)
We recently reported evidence for disturbed synaptic versus extrasynaptic NMDAR transmission in the early pathogenesis of Huntington's disease (HD), a late-onset neurodegenerative disorder caused by CAG repeat expansion in the gene encoding huntingtin. Studies in glutamatergic cells indicate that synaptic
商品
DISCOVER Bioactive Small Molecules for Neuroscience
Active Filters
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门
