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Merck

B7639

Sigma-Aldrich

生物素酰肼

≥97% (TLC), powder

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100 MG
$151.00
1 G
$768.00

About This Item

经验公式(希尔记法):
C10H18N4O2S
CAS号:
分子量:
258.34
Beilstein:
28347
MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:
NACRES:
NA.46

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质量水平

方案

≥97% (TLC)

表单

powder

溶解性

DMSO: ≤20 mg/mL

储存温度

2-8°C

SMILES字符串

[H][C@]12CS[C@@H](CCCCC(=O)NN)[C@@]1([H])NC(=O)N2

InChI

1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1

InChI key

KOZWHQPRAOJMBN-ZKWXMUAHSA-N

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一般描述

生物素酰肼是一种生物素化试剂,用于生物素化糖蛋白的糖部分 [1]。生物素酰肼可用于制备生物素标记的藻酸盐 [2]。也可通过碳二亚胺交联与 PAAc 共价连接 [3]

应用

(+)-生物素酰肼已用于:
  • 修饰海藻酸[4]
  • 标记非肌肉组织中的线粒体蛋白[5]
  • 作为糖蛋白染色液组分[6]
  • 黏液素的高碘酸-生物素-酰肼(PABH)检测[7]
  • 用于标记表面官能团、生物活性分子(如抗体、凝集素、糖、核酸或含游离羧基或酮基的分子)。
  • 通过腙形成的碳水化合物与糖蛋白偶联。

免责声明

除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、 体外 诊断用途、 离体 或 体内 治疗用途或任何类型的消费或人类或动物应用。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Boris Polyak et al.
Biomacromolecules, 5(2), 389-396 (2004-03-09)
Biotin was covalently coupled with alginate in an aqueous-phase reaction by means of carbodiimide-mediated activation chemistry to provide a biotin-alginate conjugate for subsequent use in biosensor applications. The synthetic procedure was optimized with respect to pH of the reaction medium
Studying mucin secretion from human bronchial epithelial cell primary cultures
Mucins, 259-277 (2012)
Enhanced capture and release of circulating tumor cells using hollow glass microspheres with a nanostructured surface
Dong Z, et al.
Nanoscale, 10(35), 16795-16804 (2018)
Ajay M Shah et al.
Analytical chemistry, 84(8), 3682-3688 (2012-03-15)
Microfluidic systems for affinity-based cell isolation have emerged as a promising approach for the isolation of specific cells from complex matrices (i.e., circulating tumor cells in whole blood). However, these technologies remain limited by the lack of reliable methods for
E P Diamandis et al.
Clinical chemistry, 37(5), 625-636 (1991-05-01)
The biotin-(strept)avidin system has been used for many years in a variety of different applications. Here we present a general overview of the system, describe its components and advantages, and show how the system is used in various applications, with

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