PHR1393

三水合氨苄青霉素

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 氨苄西林 三水合物, 氨苄青霉素
• 经验公式（希尔记法）: C₁₆H₁₉N₃O₄S · 3H₂O
• CAS号: 7177-48-2
• 分子量: 403.45
• Beilstein: 5399534
• EC號碼: 200-709-7
• MDL號碼: MFCD00072036
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823367
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 785; traceable to Ph. Eur. A1000000; traceable to USP 1033000/1033407
• API 家族: ampicillin
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• mp: 198-200 °C (dec.) (lit.)
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
• InChI: 1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
• InChI 密鑰: RXDALBZNGVATNY-CWLIKTDRSA-N

说明

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Ampicillin trihydrate may be used as an analytical reference standard for the determination of ampicillin in plasma samples[1] and pharmaceutical formulations[2] by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

一种具有连接到青霉素结构上的氨基侧链的 β-内酰胺抗生素。通过灭活细菌细胞膜内表面的转肽酶而抑制细菌细胞壁合成（肽聚糖交联）的青霉素衍生物。仅对生长中的大肠埃希菌具有杀菌作用。耐药方式：氨苄西林的 β-内酰胺环被 β-内酰胺酶裂解。抗菌谱：革兰阴性菌和革兰阳性菌。

腳註

To see an example of a Certificate of Analysis for this material enter LRAA1900 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H315,H317,H319,H334,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable