PHR1379

硫酸阿托品

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 阿托品 硫酸盐 一水合物, (8-甲基-8-氮杂双环[3.2.1]辛-3-基) edno-(+/-)-α-(羟甲基)苯乙酸酯, 龙葵碱
• 线性分子式: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• CAS号: 5908-99-6
• 分子量: 694.83
• Beilstein: 6109275
• EC 号: 200-235-0
• MDL编号: MFCD00074815
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329823356
• NACRES: NA.24

属性

• 等级: certified reference material; pharmaceutical secondary standard
• 质量水平: 300
• Agency: traceable to BP 23; traceable to Ph. Eur. A1400000; traceable to USP 1045009
• API类: atropine
• CofA: current certificate can be downloaded
• 技术: HPLC: suitable; gas chromatography (GC): suitable
• mp: 189-192 °C (A) (lit.)
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• 储存温度: 2-8°C
• SMILES字符串: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
• InChI key: JPKKQJKQTPNWTR-CHYDPLAESA-N
• 基因信息: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.[1]

应用

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis[2] and chromatography techniques.[3][4]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。

附注

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形图: GHS06
• 警示用语：: Danger
• 危险声明: H300 + H330
• 预防措施声明: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• 危险分类: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• 储存分类代码: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable