推荐产品
等級
analytical standard
品質等級
化驗
≥97.5%
形狀
powder
技術
HPLC: suitable
gas chromatography (GC): suitable
顏色
white
應用
forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products
格式
neat
SMILES 字串
[Cl-].C[n+]1cccc(c1)C(N)=O
InChI
1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
InChI 密鑰
BWVDQVQUNNBTLK-UHFFFAOYSA-N
一般說明
1-甲基烟酰胺(MNA)是主要由烟酰胺N-甲基转移酶(NNMT)产生的烟酰胺的主要代谢产物,具有抗血栓形成和抗炎作用。
應用
1-甲基烟酰胺氯化物可用作使用离子对反相高效液相色谱法(RP-HPLC)定量尿液样品中1-甲基烟酰胺的标准品。
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生化/生理作用
烟酸代谢的尿排泄产物
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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分析证书(COA)
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Methylnicotinamide (MNA) displays vasoprotective activity, however, the regulation of the activity of nicotinamide-N-methyltransferase (NNMT), is largely unknown. We analyze a possible involvement of IL-6 in the activation of NNMT-MNA pathway during an endurance exercise. FVB, C57Bl/6J IL6(+/+) and C57Bl/6J IL-6(-/-)
Pharmacological reports : PR, 62(3), 483-493 (2010-07-16)
Nicotinamide N-methyltransferase (NNMT), which converts nicotinamide (NA) to 1-methylnicotinamide (MNA), is up-regulated in the cirrhotic liver. Because MNA displays PGI(2)-dependent anti-inflammatory effects, the up-regulation of NNMT may play a regulatory role in liver inflammation. In the present work, we analyzed
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