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Merck

14080

Sigma-Aldrich

琥珀酸

purum p.a., ≥99.0% (T)

别名:

丁二酸

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50 G
$83.00
500 G
$84.50
1 KG
$166.00

About This Item

线性分子式:
HOOCCH2CH2COOH
CAS号:
分子量:
118.09
Beilstein:
1754069
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21

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等级

purum p.a.

质量水平

方案

≥99.0% (T)

灼烧残渣

≤0.05% (as SO4)

沸点

235 °C (lit.)

mp

184-186 °C (lit.)
185-188 °C

溶解性

methanol: soluble 0.4 g/10 mL

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

痕量阳离子

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤100 mg/kg
Na: ≤100 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

官能团

carboxylic acid

SMILES字符串

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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应用

琥珀酸可作为有机添加剂用于合成:
  • 通过铑催化与芳基肟和仲丙炔醇反应合成2-苄基取代异喹啉N-氧化物[1]
  • 通过5-(2-烷基苄基)巴比妥酸环化反应合成螺嘧啶衍生物[2]
  • 使用氢化铝锂还原硒氰酸烯丙酯,生成烯丙烯醇[3]
它也可用作反应物以合成:
  • 通过甘油和壬二酸的无催化剂聚合生成聚酯[4].
  • 聚(甘油-琥珀酸)生物树突聚合物,适用于特定医疗和生物技术用途[5]

象形图

Corrosion

警示用语:

Danger

危险声明

预防措施声明

危险分类

Eye Dam. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rhodium-Catalyzed C- H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides
Li Y, et al.
advanced synthesis and catalysis, 363, 3305-3310 (2021)
Chih-Zen Chang et al.
BioMed research international, 2015, 490209-490209 (2015-11-06)
Upregulation of protein kinase B (PKB, also known as Akt) is observed within the cerebral arteries of subarachnoid hemorrhage (SAH) animals. This study is of interest to examine Arctigenin, a potent antioxidant, on endothelial nitric oxide synthase (eNOS) and Akt
Hydride transfer reactions of 5-(2-alkohybenzylidene) barbituric acids: Synthesis of 2, 4, 6-trioxoperhydropyrimidine-5-spiro-3?-chromanes
Krasnov K, et al.
Tetrahedron, 73, 542-549 (2017)
Synthesis and characterization of polyesters derived from glycerol, azelaic acid, and succinic acid
Baharu M, et al.
Green Chemistry Letters and Reviews, 8, 31-38 (2015)
Harald Møllendal et al.
The journal of physical chemistry. A, 113(22), 6342-6347 (2009-05-08)
The microwave spectrum of 2-propene-1-selenol, H(2)C=CHCH(2)SeH, has been investigated in the 45-80 GHz spectral range at -30 degrees C. The spectra of six isotopologues of one conformer, which has an anticlinal orientation for the C=C-C-Se chain of atoms and a

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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