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810255P

Avanti

TopFluor胆固醇

Avanti Research - A Croda Brand

别名:

Bodipy胆固醇;Bdp-Chol

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1 MG
$370.00
5 MG
$758.00
10 MG
$1,370.00

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1 MG
$370.00
5 MG
$758.00
10 MG
$1,370.00

About This Item

经验公式(希尔记法):
C36H51BF2N2O
分子量:
576.61
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25

$370.00


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描述

23-(dipyrrometheneboron difluoride)-24-norcholesterol

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 1 mg (810255P-1mg)
pkg of 1 × 10 mg (810255P-10mg)
pkg of 1 × 5 mg (810255P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

一般描述

附着在BODIPY上的生物分子在可见光下很容易被吸收。它导致更大的荧光量子产率。它具有很高的光稳定性,并且对极性和pH的变化不太敏感。[1]

应用

TOPFLUOR适用于:
  • 胆固醇摄取测定[2]
  • 在活细胞实验中用于BODIPY胆固醇标记[3]
  • 通过聚乙烯醇(PVA)辅助的脂质溶胀形成巨大的Janus脂质体 [4]

生化/生理作用

BODIPY标记的胆固醇具有与天然胆固醇相似的特性。[5]它可充当活细胞的胆固醇标志物,[1]并有助于运输细胞内的胆固醇。[5]它也可能有助于指示脂质储存疾病。[1]

包装

5 mL棕色玻璃螺旋盖小瓶(810255P-10mg)
5 mL棕色玻璃螺旋盖小瓶(810255P-1mg)
5 mL棕色玻璃螺旋盖小瓶(810255P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jameson T Crowley et al.
PLoS pathogens, 9(1), e1003109-e1003109 (2013-01-18)
Borrelia burgdorferi, the agent of Lyme disease, has cholesterol and cholesterol-glycolipids that are essential for bacterial fitness, are antigenic, and could be important in mediating interactions with cells of the eukaryotic host. We show that the spirochetes can acquire cholesterol
James E Shaw et al.
Biophysical journal, 90(6), 2170-2178 (2005-12-20)
Coupling atomic force microscopy (AFM) with high-resolution fluorescence microscopy is an attractive means of identifying membrane domains by both physical topography and fluorescence. We have used this approach to study the ability of a suite of fluorescent molecules to probe
Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens
Cockburn CL, et al.
Life science alliance, 2(2), e201800292-e201800292 (2019)
Katarina Trajkovic et al.
Science (New York, N.Y.), 319(5867), 1244-1247 (2008-03-01)
Intraluminal vesicles of multivesicular endosomes are either sorted for cargo degradation into lysosomes or secreted as exosomes into the extracellular milieu. The mechanisms underlying the sorting of membrane into the different populations of intraluminal vesicles are unknown. Here, we find
Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure
Solanko LM, et al.
Biophysical Journal, 105(9), 2082-2092 (2013)

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