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Merck

144916

Sigma-Aldrich

2-氨基-5-甲基苯酚

98%

别名:

2-羟基-4-甲基苯胺, 4-氨基-3-羟基甲苯, 6-氨基间甲酚

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About This Item

线性分子式:
H2NC6H3(CH3)OH
CAS号:
分子量:
123.15
Beilstein:
386144
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
形狀:
powder
化驗:
98%

化驗

98%

形狀

powder

mp

159-162 °C (lit.)

SMILES 字串

Cc1ccc(N)c(O)c1

InChI

1S/C7H9NO/c1-5-2-3-6(8)7(9)4-5/h2-4,9H,8H2,1H3

InChI 密鑰

HCPJEHJGFKWRFM-UHFFFAOYSA-N

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一般說明

2-氨基-5-甲酚与牛血红蛋白反应生成 2-氨基-4,4α-二氢-4α-7-二甲基-3 H -吩恶嗪-3-酮,它抑制脊髓灰质炎病毒在 Vero 细胞中的增殖 。它通过经纯化的人血红蛋白转化为二氢吩恶嗪酮

應用

2-氨基-5-甲酚用于采用苯氧基亚胺配体进行三齿席夫碱配体和新型非茂金属催化剂的合成

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Akiko Iwata et al.
The Tohoku journal of experimental medicine, 200(3), 161-165 (2003-10-03)
2-Amino-4,4alpha-dihydro-4alpha-7-dimethyl-3H-phenoxazine-3-one (Phx), which was produced by the reaction of bovine hemoglobin with 2-amino-5-methylphenol, inhibited the proliferation of poliovirus in Vero cells between 0.25 microg/ml and 2 microg/ml with maximal antiviral acitivity at 1 microg/ml. These results suggest that Phx may
The investigation of novel non-metallocene catalysts with phenoxy-imine ligands for ethylene (co-) polymerization.
Zhang X, et al.
Polymer International, 62(3), 419-426 (2012)
Synthesis,structural characterization and catalytic activity study of Mn(II), Fe(III), Ni(II), Cu(II) and Zn(II) complexes of quinoxaline-2-carboxalidine-2-amino-5-methylphenol: Crystal structure of the nickel (II) complex.
Sebastian M, et al.
Polyhedron, 29(15), 3014-3020 (2010)
A Tomoda et al.
Biochimica et biophysica acta, 1117(3), 306-314 (1992-10-27)
We found that 2-amino-5-methylphenol was converted to the dihydrophenoxazinone with a reddish brown color by purified human hemoglobin, lysates of human erythrocytes, and human erythrocytes. The reddish brown compound was identified as 2-amino-4,4 alpha-dihydro-4 alpha,7-dimethyl-3H-phenoxazin-3-one by the measurement of NMR
A Tomoda et al.
Bioorganic & medicinal chemistry letters, 11(8), 1057-1058 (2001-05-01)
A simple and rapid preparation method for a novel antitumor agent, 2-amino-4,4a-dihydro-4a,7-dimethyl-3H-phenoxazine-3-one (Phx) was described. The procedure included (1) the reaction of bovine hemolysates with 2-amino-5-methylphenol, (2) one-shot denaturation of hemoglobin and proteins by methanol, and removal of the denatured

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