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Merck

552224

Sigma-Aldrich

2-氨基-5-氯苯酚

97%

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5 G
$44.20

About This Item

线性分子式:
H2NC6H3(Cl)OH
CAS号:
分子量:
143.57
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

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质量水平

方案

97%

表单

solid

mp

145-153 °C (lit.)

官能团

chloro

SMILES字符串

Nc1ccc(Cl)cc1O

InChI

1S/C6H6ClNO/c7-4-1-2-5(8)6(9)3-4/h1-3,9H,8H2

InChI key

FZCQMIRJCGWWCL-UHFFFAOYSA-N

一般描述

2-Amino-5-chlorophenol can be synthesized from 2-chloro-5-nitrophenol via reduction.[1] It can also be obtained from 1-chloro-4-nitrobenzene by using a bacterial strain LW1.[2] 2-Amino-5-chlorophenol participates in the condensation reaction with acetylferrocene to afford ferrocenyl Schiff bases bearing a phenol group.[3]

应用

2-Amino-5-chlorophenol may be used to synthesize 2-amino-5-chloromuconic semialdehyde[4] and benzoxazole derivatives.[5]

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jian-Feng Wu et al.
Archives of microbiology, 183(1), 1-8 (2004-12-08)
Comamonas strain CNB-1 was isolated from a biological reactor treating wastewater from a p-chloronitrobenzene production factory. Strain CNB-1 used p-chloronitrobenzene as sole source of carbon, nitrogen, and energy. A 2-aminophenol 1,6-dioxygenase was purified from cells of strain CNB-1. The purified
Synthesis and Crystal Structure of 1-Chloro-2-methyl-4-nitrobenzene.
Saeed A and Simpson J.
Crystals, 2(1), 137-143 (2012)
Synthesis, characterization, and antimicrobial activity of cobalt (II), nickel (II), copper (II) and zinc (II) complexes with ferrocenyl Schiff bases containing a phenol moiety.
Abd-Elzaher MM.
Applied Organometallic Chemistry, 18(4), 149-155 (2004)
Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases.
Wisastra R, et al.
Bioorganic & Medicinal Chemistry, 20(12), 5027-5032 (2012)
M Valentovic et al.
Toxicology and applied pharmacology, 161(1), 1-9 (1999-11-24)
2-Amino-5-chlorophenol is nephrotoxic through an unidentified mechanism. This study examined the in vitro toxicity of 2-amino-5-chlorophenol in renal cortical slices from Fischer 344 rats and specifically assessed induction of lipid peroxidation and depletion of renal glutathione. Renal cortical slices exposed

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