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Merck

115533

Sigma-Aldrich

1,1′-羰基二咪唑

greener alternative

≥90.0% (proton, NMR), for peptide synthesis

别名:

CDI

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5 G
$60.80
10 G
$93.70
25 G
$182.00
100 G
$544.00
500 G
$1,030.00
1 KG
$1,400.00
25 KG
$20,570.00

$60.80


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选择尺寸

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5 G
$60.80
10 G
$93.70
25 G
$182.00
100 G
$544.00
500 G
$1,030.00
1 KG
$1,400.00
25 KG
$20,570.00

About This Item

经验公式(希尔记法):
C7H6N4O
CAS号:
分子量:
162.15
Beilstein:
6826
EC 号:
MDL编号:
UNSPSC代码:
12352115
PubChem化学物质编号:
NACRES:
NA.22

$60.80


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产品名称

1,1′-羰基二咪唑, reagent grade

等级

reagent grade

质量水平

方案

≥90.0% (proton, NMR)

表单

solid

反应适用性

reaction type: Carbonylations

环保替代产品特性

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

117-122 °C (lit.)

应用

peptide synthesis

环保替代产品分类

SMILES字符串

O=C(n1ccnc1)n2ccnc2

InChI

1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H

InChI key

PFKFTWBEEFSNDU-UHFFFAOYSA-N

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一般描述

我们致力于为您提供更环保的替代产品,以符合“绿色化学的12项原则”的一项或多项原则要求。1,1′-羰基咪唑(CDI)是剧毒毒物光气的替代品,因此符合“设计更安全化学品”的原则。更多信息,请参见利用咪唑羧酸酯高选择性反应控制合成不对称二烷基和环碳酸酯

应用

用于合成偶极聚酰胺和多肽的偶联剂,偶极聚酰胺具有非线性光学用途[1][2]也可用于制备 β-酮砜和亚砜、[3]铅螯合剂[4]和 β-烯胺酸衍生物。[5]

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Polym. Mater. Sci. Eng., 61, 936-936 (1989)
The Journal of Organic Chemistry, 54, 5620-5620 (1989)
Inorganic Chemistry, 32, 3052-3052 (1993)
Tetrahedron Letters, 34, 725-725 (1993)
A B Cheikh et al.
Journal of molecular evolution, 30(4), 315-321 (1990-04-01)
We have prepared the nucleoamino acids 1-(3'-amino,3'-carboxypropyl)uracil (3) and 9-(3'-amino,3'-carboxypropyl)adenine (4) as (L)-enantiomers and as racemic mixtures. When 3 or 4 is suspended in water and treated with N,N'-carbonyldiimidazole, peptides are formed in good yield. The products formed from the

商品

N-Acylimidazoles and carbonylimidazoles are reactive intermediates used for amino compound acylation, surpassing DCC as coupling reagents.

相关内容

N-Acylimidazoles were recognized in the early 1950s as reactive intermediates suitable for the acylation of amino compounds. The search for better coupling reagents than DCC led to the development of CDI (1,1’-carbonyldiimidazole) and related carbonylimidazoles.

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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