SRP5353

IRAK3, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Synonim(y): IRAK-M
• Kod UNSPSC: 12352200
• NACRES: NA.32

Właściwości

• rekombinowane: expressed in baculovirus infected Sf9 cells
• Próba: ≥70% (SDS-PAGE)
• Postać: buffered aqueous glycerol solution
• masa cząsteczkowa: ~96 kDa
• numer dostępu NCBI: BC057800
• Warunki transportu: dry ice
• temp. przechowywania: −70°C
• informacje o genach: human ... IRAK3(11213)

Opis

Opis ogólny

IRAK3 or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which is essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAKM mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.

Postać fizyczna

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Uwaga dotycząca przygotowania

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable