SML0396

Tafenoquine succinate

≥95% (HPLC), primaquine analog, powder

• Synonim(y): N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine, SB-252263, WR 238605
• Wzór empiryczny (zapis Hilla): C₂₄H₂₈F₃N₃O₃ · C₄H₆O₄
• Numer CAS: 106635-81-8
• Masa cząsteczkowa: 581.58
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825392
• NACRES: NA.77
• MDL number: MFCD00892249
• Assay: ≥95% (HPLC)
• Form: powder
• Quality level: 100
• Storage condition: desiccated

Właściwości

• Nazwa produktu: Tafenoquine succinate, ≥95% (HPLC)
• SMILES string: OC(=O)CCC(O)=O.COc1cc(C)c2c(Oc3cccc(c3)C(F)(F)F)c(OC)cc(NC(C)CCCN)c2n1
• InChI: 1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8)
• InChI key: CQBKFGJRAOXYIP-UHFFFAOYSA-N
• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 5 mg/mL (clear solution)
• storage temp.: 2-8°C
• Quality Level: 100

Opis

Biochem/physiol Actions

Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.

Tafenoquine is an antimalarial.

Tafenoquine has been generally generated for oral administration and drug absorption increases when taken along with food. It is known to possess a longer half life.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable