RAB0874

Porcine INS / Insulin ELISA Kit

• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: Porcine ... INS(397415)
• Input: sample type plasma; sample type cell culture supernatant(s); sample type serum
• Species reactivity: porcine
• Storage temp.: −20°C
• Shipped in: wet ice

Właściwości

• species reactivity: porcine
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type plasma; sample type cell culture supernatant(s); sample type serum
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 4 μIU/mL; standard curve range: 4.69 μIU/ml-300 μIU/ml
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: Porcine ... INS(397415)

Opis

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Abnormal insulin secretion or function, leads to diabetes mellitus, obesity and other carbohydrate metabolism disorders.[1][2] Insulin is known to stimulate cell division. The biological effects of insulin are mediated by insulin receptor and it integrates major signaling pathways.[1]

General description

The antibody reacts specifically against insulin by RIA and immunocytochemistry.[3][4][5] It exhibits cross-reactivity with human proinsulin.[5] The antibody binds to insulin with an affinity constant of 8.8 × 10⁹ M^-1 in RIA.[3][4] The insulin gene is mapped to human chromosome 11p15.5.[6]
Human insulin is made up of 51 amino acids. It consists of two peptide chains, 21 amino acids make up A-chain and chain B contains 31 amino acids. The two chains are linked together by a disulfide bond, to form a classical insulin fold with three α helices, chain A having two and one in chain B.[7]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Elementy zestawu są też dostępne oddzielnie

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABWASH4 20X Wash Buffer (Item B)

Informacja o środkach bezpieczeństwa

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Klasa składowania: 8A - Combustible corrosive hazardous materials
• flash_point_f: Not applicable
• flash_point_c: Not applicable