RAB0780
Mouse Tyro3 / Tyrosine-protein Kinase Receptor TYRO3 ELISA Kit
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Informacje o tej pozycji
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Tyro3(22174)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type serum
sample type plasma
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
Pomoc techniczna
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Pozwól nam pomócPomoc techniczna
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Pozwól nam pomócspecies reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.4 ng/mL
standard curve range: 0.416-100 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Tyro3(22174)
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General description
The antibody pair provided in this kit recognizes mouse Tyro3.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Tyrosine-protein kinase receptor (TYRO3) is a transmembrane tyrosine kinase receptor. It plays a significant role in the brain development during embryogenesis. It plays an important role in apoptotic cell clearance. In hepatocellular carcinoma, it is associated with tumor growth, aggressiveness and liver dysfunction. Mutations in the TYRO3 gene intronic regions are linked with asthma. TYRO3 is also a suppressor of type 2 immunity. As part of the TAM (TYRO3, AXL and MER receptors) family, it is activated by PROS1 (protein S) and GAS6 (growth arrest-specific gene 6). Changes in the expression of TYRO3 are linked with the proliferation and survival of cancer cells. Absence of TYRO3 in mice results in neurological disorders.
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Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Klasa składowania
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
The Gas6/TAM System and Multiple Sclerosis.
Bellan M, et al.
International Journal of Molecular Sciences, 17 (2016)
Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.
Tsou WI
The Journal of Biological Chemistry, 289, 25750-25763 (2014)
Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in juvenile-onset systemic lupus erythematosus.
Ballantine L, et al.
Pediatric Rheumatology Online Journal (2015)
Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression.
Duan Y
International Journal of Oncology, 48, 358-366 (2016)
The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity.
Chan PY
Science, 352, 99-103 (2016)
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| RAB0780-1KT | 04061835165629 |
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