R6527

Reboxetine mesylate hydrate

>96% (HPLC), noradrenaline uptake inhibitor, solid

• Synonim(y): (2R)-rel-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine, Edronax, Vestra
• Wzór empiryczny (zapis Hilla): C₁₉H₂₃NO₃ · CH₃SO₃H · xH₂O
• Numer CAS: 98769-84-7
• Masa cząsteczkowa: 409.50 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724592
• NACRES: NA.77
• MDL number: MFCD11046031
• Assay: >96% (HPLC)
• Form: solid
• Storage condition: desiccated

Właściwości

• Nazwa produktu: Reboxetine mesylate hydrate, >96% (HPLC), solid
• Quality Segment: 100
• assay: >96% (HPLC)
• form: solid
• storage condition: desiccated
• color: white to tan
• solubility: H₂O: >5 mg/mL at ≤60 °C
• shipped in: wet ice
• storage temp.: 2-8°C
• SMILES string: O.CS(O)(=O)=O.CCOc1ccccc1O[C@@H]([C@H]2CNCCO2)c3ccccc3
• InChI: 1S/C19H23NO3.CH4O3S.H2O/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4;/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4);1H2/t18-,19-;;/m1../s1
• InChI key: SZPHEVAYLIVGRC-BAMQSBMESA-N

Opis

Application

Reboxetine mesylate hydrate has been used as a selective norepinephrine transport blocker:

• to study its effects on the surge of dopamine in the cortex of mice brain[1]
• to study its anti-immobility effects on the behavior of mice[2]
• to analyze its effects on the probabilistic reversal learning task in rodents[3]

Biochem/physiol Actions

Reboxetine mesylate hydrate is a selective noradrenaline uptake inhibitor.

Reboxetine exhibits anti-depressant activity.[1]

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)