P5155

D-Pantothenic acid hemicalcium salt

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

• Synonim(y): (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, Calcium D-pantothenate, Vitamin B₅
• Wzór liniowy: HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• Numer CAS: 137-08-6
• Masa cząsteczkowa: 238.27
• NACRES: NA.75
• PubChem Substance ID: 24898601
• eCl@ss: 34058012
• UNSPSC Code: 12352205
• EC Number: 205-278-9
• MDL number: MFCD00002766
• Beilstein/REAXYS Number: 3769272
• Assay: ≥98% (TLC)
• Form: powder
• Quality level: 200

Właściwości

• InChI key: FAPWYRCQGJNNSJ-UBKPKTQASA-L
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
• SMILES string: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• biological source: synthetic (organic)
• product line: BioReagent
• assay: ≥98% (TLC)
• form: powder
• mol wt: M_w 238.27 g/mol
• technique(s): cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable
• color: white to off-white
• pH: 7.0-8 (25 °C, 50 g/L)
• solubility: water: soluble 50 mg/mL, clear, colorless
• storage temp.: 2-8°C
• Quality Level: 200

Opis

General description

Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.

Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid.[1] It is water soluble[2] and quite stable to heating.[3]

Application

D-Pantothenic acid hemicalcium salt has been used:

• as a component of FMX-turbodoma- derived media[2]
• as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation[4]
• as a supplement in preadipocyte media[5]

Precursor in the biosynthesis of coenzyme A.

Biochem/physiol Actions

Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein.[1] These are essential cofactors[1] involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.[3]

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)