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C8731

Calcium pantothenate

meets USP testing specifications, monograph mol wt. 476.53 (C18H32CaN2O10)

Synonim(y):

D-Pantothenic acid hemicalcium salt, (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine, Calcium D-pantothenate, Vitamin B5

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Rozmiar/SKUDostępnośćCena netto
25 g
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634,00 zł
100 g
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2110,00 zł
1 kg
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16 310,00 zł

Informacje o tej pozycji

Wzór liniowy:
HOCH2C(CH3)2CH(OH)CONHCH2CH2CO2 ·1/2Ca
Numer CAS:
Masa cząsteczkowa:
476.53
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
34058012
UNSPSC Code:
12352205
EC Number:
205-278-9
MDL number:
Beilstein/REAXYS Number:
3769272

634,00 zł


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biological source

synthetic (organic)

Quality Segment

agency

USP/NF, meets USP testing specifications

form

crystalline, powder

mol wt

monograph mol wt. 476.53 (C18H32CaN2O10)

technique(s)

cell culture | mammalian: suitable, cell culture | plant: suitable

color

white

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1

InChI key

FAPWYRCQGJNNSJ-UBKPKTQASA-L

General description

Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.
Vitamin B5 or pantothenic acid is a viscous oil that is soluble in ethanol and water. It is produced by plants and microorganisms. d-(+)pantothenic acid is the naturally occurring form of pantothenic acid and is biologically active.

Application

Precursor in the biosynthesis of coenzyme A.
Calcium pantothenate has been used:
  • as a component of vitamin solution for synthetic media
  • as a component of vitamin mix for the ICS medium mix
  • as a component of a chemically defined diet for metal depletion studies in Drosophila
  • as a supplement to study coenzyme A metabolism in mouse models of non-alcoholic steatohepatitis

Biochem/physiol Actions

The calcium salts of panthenol are commonly used for pharmaceutical preparations. Pantothenate is a component of coenzyme A and is useful in its synthesis. Pantothenic acid is also involved in the synthesis of heme, cholesterol and fatty acids. Since vitamin B5 is found in all foods, its deficiency is not commonly observed.
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Ta pozycja
1087009C0400000PHR1232
description

meets USP testing specifications, monograph mol wt. 476.53 (C18H32CaN2O10)

description

United States Pharmacopeia (USP) Reference Standard

description

European Pharmacopoeia (EP) Reference Standard

description

Pharmaceutical Secondary Standard; Certified Reference Material

technique(s)

cell culture | plant: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

biological source

synthetic (organic)

biological source

-

biological source

synthetic

biological source

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

form

powder, crystalline

form

-

form

solid

form

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

300


Klasa składowania

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. Quelle est la solubilité de ce produit ?

    1 answer
    1. Solubility is not tested internally, but it is considered freely soluble in water (up to about 350 mg/mL). It is also very slightly soluble in ethanol and methanol.

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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