Przejdź do
K1632
Kininogen high molecular weight, Two Chain from human plasma
lyophilized powder
Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.
Wybierz wielkość
Zmień widok
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 0.1 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 465,00 zł |
Informacje o tej pozycji
Form:
lyophilized powder
Biological source:
human plasma
465,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.
Pozwól nam pomócbiological source
human plasma
Quality Level
form
lyophilized powder
solubility
H2O: soluble 0.1 mg protein/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... KNG1(3827), KNG1 (includes EG:3827)
1 of 1
Ta pozycja | |||
|---|---|---|---|
| biological source human plasma | biological source human plasma | biological source - | biological source human plasma |
| form lyophilized powder | form lyophilized powder | form liquid | form lyophilized powder |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. - | UniProt accession no. |
| solubility H2O: soluble 0.1 mg protein/mL | solubility - | solubility - | solubility water: soluble ≥0.500 mg/mL, clear to slightly hazy, colorless |
| storage temp. −20°C | storage temp. −20°C | storage temp. −70°C | storage temp. −20°C |
| Gene Information human ... KNG1(3827), KNG1 (includes EG:3827)(3827) | Gene Information human ... HPX(3263) | Gene Information - | Gene Information human ... FN1(2335) |
General description
HK (KNG1) gene is mapped to human chromosome 3q27.3. It is a glycoprotein.[1]
High-molecular-weight kininogen (HK) is the substrate and cofactor of the plasma kallikrein-kinin system (KKS). It is present at a concentration of 660 nM on the plasma and binds to platelet GPI-V-IX complex.
Biochem/physiol Actions
High molecular weight kininogen, two chain, is a participant in contact phase activation of the intrinsic blood coagulation cascade that forms a substrate on which blood factor XI is held in proximity to factor XII allowing reciprocal activation of the two factors. It is also involved in the activation of prekallikrein. High molecular weight kininogen binds to proteoglycans on the surface of platelets, endothelial cells, and other cell types. Domain 5 of high molecular weight kininogen inhibits platelet aggregation and angiogenesis.
High-molecular-weight kininogen (HK) inhibits binding of thrombin to platelets.[2]
Packaging
Package size based on protein content
Physical form
Lyophilized from 4 mM sodium acetate, pH 5.3, 0.15 M NaCl
Preparation Note
Prepared by kallikrein digestion of human kininogen. Purified to remove kallikrein and kinin.
Ta strona może zawierać tekst przetłumaczony maszynowo.
Klasa składowania
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Wybierz jedną z najnowszych wersji:
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Henri Weidmann et al.
Biochimica et biophysica acta. Molecular cell research, 1864(11 Pt B), 2118-2127 (2017-07-27)
The contact system is a potent procoagulant and proinflammatory plasma protease cascade that is initiated by binding ("contact")-induced, auto-activation of factor XII zymogen. Formed active serine protease FXIIa then cleaves plasma prekallikrein to kallikrein that in turn liberates the mediator
[Omeprazole long-term therapy: how great is the risk of developing a carcinoid tumor?].
H Koop
Zeitschrift fur Gastroenterologie, 26(12), 769-771 (1988-12-01)
Rince John et al.
FEBS letters, 591(21), 3507-3522 (2017-09-28)
Cytoglobin (Cygb) is a cellular haemoprotein belonging to the globin family with ambiguous biological functions. Downregulation of Cygb in many cancers is indicative of its tumour-suppressive role. This is the first report showing the cell cycle regulation of Cygb, which
Thomas Koudstaal et al.
American journal of respiratory cell and molecular biology, 63(5), 665-680 (2020-08-07)
Chronic perivascular inflammation is a prominent feature in the lungs of idiopathic pulmonary arterial hypertension. Although the proportions of conventional dendritic cells (cDCs) and plasmacytoid DCs are increased in idiopathic pulmonary arterial hypertension lungs, it remains unknown whether activated cDCs
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| K1632-.1MG | 04061833421086 |
Active Filters
Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.
Skontaktuj się z zespołem ds. pomocy technicznej