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F5386

Sigma-Aldrich

Fibrin from human plasma

insoluble powder

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1 G
2610,00 zł

2610,00 zł


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1 G
2610,00 zł

About This Item

Numer CAS:
Numer WE:
Numer MDL:
Kod UNSPSC:
12352202
NACRES:
NA.61

2610,00 zł


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pochodzenie biologiczne

human plasma

Formularz

powder

metody

indirect ELISA: suitable

numer dostępu UniProt

ciąg SMILES

N(CC(=O)NC)C(=O)CN

InChI

1S/C5H11N3O2/c1-7-5(10)3-8-4(9)2-6/h2-3,6H2,1H3,(H,7,10)(H,8,9)

Klucz InChI

BWGVNKXGVNDBDI-UHFFFAOYSA-N

informacje o genach

Opis ogólny

Fibrin is produced from cross-linking of fibrinogen by thrombin. Fibrinogen is made up of two monomers each containing three polypeptide chains. Fibrinogen is a major plasma protein.

Zastosowanie

Fibrin from human plasma has been used:
  • for in vitro cleavage of fibrinogen and fibrin
  • as a reference for true component analysis (TCA) and principal component analysis (PCA) of Raman spectra
  • as a reference in Raman spectroscopy to study the binding mechanisms and the binding efficiency of the different polyoxometalates (POMs)

Działania biochem./fizjol.

Fibrin acts as an important bio-polymer in the primary blood clotting process. It creates a scaffold for infiltrating cells during tissue repair. Fibrin is widely used as a tissue sealant for tissue regeneration applications as it enables the formation of a biocompatible physical structure. It is also used in delivery systems for cells and bioactive molecules. The fibrin matrix resembles the native pancreas and can serve as a scaffold material for islet transplantation. Fibrin has been used in studies to obtain fibrin-specific monoclonal antibodies (mAbs). These mAbs may be used to determine their role in fibrin polymerization and use in fibrin quantification in blood plasma.

Uwaga dotycząca przygotowania

Prepared by clotting fibrinogen to yield a crosslinked fibrin

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Produkty

Cell based angiogenesis assays to analyze new blood vessel formation for applications of cancer research, tissue regeneration and vascular biology.

Testy angiogenezy oparte na komórkach do analizy tworzenia nowych naczyń krwionośnych do zastosowań w badaniach nad rakiem, regeneracji tkanek i biologii naczyniowej.

Highlighting existing and novel fabrication methods for both, solid and hydrogel-based scaffold for tissue engineering applications.

Omówiono biomateriały na bazie hydrożeli do dostarczania komórek i regeneracji tkanek.

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Questions

  1. hi, I wonder what's the molecular mass of the fibrin you provide. I would appreciate it if you can offer me answer as soon as possible.

    1 answer
    1. The molecular weight for this product is not determined. It is considered to be a cross-linked form. Various publications site this type of fibrin having a ranging anywhere from 80kDa to 300kDa or more.

      Helpful?

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