MAB5578
Anti-NMDAR2D Antibody
ascites fluid, clone 1G9.39A5, Chemicon®
Wybierz wielkość
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 μL | Dostępne do wysyłki DZISIAJzKuehne + Nagel Sp. z o.o. | 2060,00 zł |
Informacje o tej pozycji
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
ascites fluid
clone
1G9.39A5, monoclonal
species reactivity
human, mouse, rat, rabbit
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GRIN2D(2906)
Immunogen
Application
Neuroscience
Neurotransmitters & Receptors
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Physical form
Preparation Note
Analysis Note
Rat forebrain or cerebellum.
Legal Information
Disclaimer
1 of 1
Ta pozycja | |||
|---|---|---|---|
| Gene Information human ... GRIN2D(2906) | Gene Information - | Gene Information - | Gene Information human ... GRIN2A(2903) |
| clone 1G9.39A5, monoclonal | clone 1E4.25A4, monoclonal | clone 1A8.9B3, monoclonal | clone monoclonal |
| antibody form ascites fluid | antibody form ascites fluid | antibody form ascites fluid | antibody form affinity purified immunoglobulin |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| species reactivity human, mouse, rat, rabbit | species reactivity mouse, rabbit, rat | species reactivity human, rabbit, fish, rat, mouse | species reactivity human |
Klasa składowania
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Powiązane treści
Glutamate is an excitatory neurotransmitter found in the synaptic vesicles of glutamatergic synapses. The post-synaptic neurons in these synapses contain ionotropic and metabotropic glutamate receptors. Glutamate binds to AMPA (α-amino-3-hydroxy-5- methylisoxazole-4-propionic acid) subtype glutamate receptors, leading to sodium influx into the post-synaptic cell and resulting in neuronal excitability and synaptic transmission. The NMDA (N-methyl-d-aspartate) subtype glutamate receptors, on the other hand, regulate synaptic plasticity, and can influence learning and memory. The metabotropic g-protein coupled mGluRs modulate downstream calcium signaling pathways and indirectly influence the synapse’s excitability. The synaptic architecture includes intracellular scaffolding proteins (PSD-95, GRIP), intercellular cell adhesion molecules (NCAMs, N-Cadherins), and a variety of signaling proteins (CaMKII/PKA, PP1/PP2B). Processes critical for synaptic transmission and plasticity are influenced by these molecules and their interactions. When the function of these molecules is disrupted, it leads to synaptic dysfunction and degeneration, and can contribute to dementia as seen in Alzheimer’s disease.
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| MAB5578 | 04053252616570 |