The Human CD8 Milliplex kit is quite stable when stored at room temperature or 37°C for up to 7 days. Although mean fluorescent intensities (MFIs) may experience a slight depression when stored at 37°C as opposed to 4°C, this difference is not typically significant. Additionally, there may be a slight decrease in sensitivity for some analytes, but it generally remains below the reported minimum detectable concentration (minDC) plus two standard deviations (2SD).
HCD8MAG-15K
MILLIPLEX® Human CD8+ T Cell Magnetic Bead Panel - Immunology Multiplex Assay
MILLIPLEX® Human CD8+ T Cell Magnetic Bead Panel - Immunology Multiplex Assay
Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.
Synonim(y):
10549 test immunologiczny na ludzkie cytokiny, Panel cytokin ludzkich komórek T CD8, Panel ludzkich cytokin Millipore, Zestaw multipleksowy ludzkich cytokin
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About This Item
Kod UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Polecane produkty
Poziom jakości
reaktywność gatunkowa
human
producent / nazwa handlowa
Milliplex®
assay range
standard curve range: 0.4-1,500 pg/mL
(IL-6)
standard curve range: 0.5-2,000 pg/mL
(TNFα)
standard curve range: 1-3,500 pg/mL
(MIP-1α)
standard curve range: 1-5,000 pg/mL
(Granzyme B)
standard curve range: 1-5,000 pg/mL
(IFNγ)
standard curve range: 1-5,000 pg/mL
(IL-5)
standard curve range: 10-50,000 pg/mL
(Perforin)
standard curve range: 10-50,000 pg/mL
(sFasL)
standard curve range: 2-10,000 pg/mL
(IL-4)
standard curve range: 2-10,000 pg/mL
(sCD137)
standard curve range: 2-7,500 pg/mL
(IL-13)
standard curve range: 2-7,500 pg/mL
(IL-2)
standard curve range: 20-100,000 pg/mL
(Granzyme A)
standard curve range: 4-15,000 pg/mL
(GM-CSF)
standard curve range: 400-1,650,000 pg/mL
(sFas)
standard curve range: 5-20,000 pg/mL
(IL-10)
standard curve range: 7-30,000 pg/mL
(MIP-1β)
metody
multiplexing: suitable
metoda wykrywania
fluorometric (Luminex xMAP)
Warunki transportu
wet ice
Opis ogólny
CD8+ T cells (also known as cytotoxic T cells, cytolytic T cells and killer T cells) belong to a sub-group of T cells capable of inducing the death of infected somatic or tumor cells. T cells that bind weakly to Major Histocompatibility Complex (MHC) self-antigens are positively selected into single-positive CD4+ or CD8+ T cells in the thymus. Those CD8+ T cells that survive and mature after activation become cytotoxic cells, expressing T-cell receptors (TCRs) capable of recognizing specific antigenic peptides bound to Class I MHC molecules and the glycoprotein CD8. Affinity between the CD8 protein and the MHC molecule helps to keep the cytotoxic T cell and target closely bound during antigen specific activation. Once activated, CD8+ T cells are generally classified as having a predefined cytotoxic role within the immune system and undergo IL-2 induced clonal expansion, which increases the number of cells specific for the target antigen. The CD8+ T cells then travel throughout the body in search of antigen-positive somatic/tumor cells.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
Specyficzność
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Zastosowanie
- Analytes: GM-CSF, sCD137, IFNγ, sFas, sFasL, Granzyme A, Granzyme B, IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, MIP-1α, MIP-1β, TNF-α, Perforin
- Recommended Sample type: serum, plasma or tissue/cell lysate and culture supernatant
- Recommended Sample dilution: Neat
- Assay Run Time: Overnight
- Research Category Inflammation & Immunology
Cechy i korzyści
Design your multiplex kit by choosing available analytes within this panel.
Przechowywanie i stabilność
Recommended storage for kit components is 2 - 8°C.
Inne uwagi
Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.
Informacje prawne
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Organy docelowe
Respiratory Tract
Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
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Powiązane treści
See how multiplexing the inflammation signaling pathway with MILLIPLEX® inflammation assays or cell signaling assays can help researchers bridge the gap between immunology and cell signaling, including investigating T cell signaling, Th Cell differentiation, inflammatory response signaling, and sepsis signaling.
Immunology multiplex assays, like MILLIPLEX® assays, allow researchers to investigate more immune biomarkers simultaneously, saving time and resources. This is especially critical to immunology research, where numerous analytes play a role in different pathways.
Immunologiczne testy multipleksowe, takie jak testy MILLIPLEX®, pozwalają badaczom na jednoczesne badanie większej liczby biomarkerów immunologicznych, oszczędzając czas i zasoby. Jest to szczególnie istotne w badaniach immunologicznych, w których wiele analitów odgrywa rolę w różnych szlakach.
Odkryj zalety testów multipleksowych MILLIPLEX®, opartych na technologii testów multipleksowych Luminex® xMAP®, które zapewniają spójne, wysokiej jakości wyniki i zobacz, w jaki sposób te multipleksowe testy biomarkerów Luminex® są wykorzystywane do postępu badań.
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