Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defense against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
Specyficzność
This isotype control shows negligible cross-reactivity with human cell surface antigens on tissue sections or in cellular preparations. It therefore enables the estimation of non-specific binding of mouse monoclonals to cell surface antigens.
Zastosowanie
Mouse IgG1 Negative Control Monoclonal Antibody validated for use in Flow Cytometry.
Research Category Secondary & Control Antibodies
Research Sub Category Epitope Tags
Jakość
Evaluated by Flow Cytometry in HeLa cells. Flow Cytometry Analysis: 2 µg of this antibody was used as a Mouse IgG1 Negative Control in staining of HeLa cells.
Powiązanie
Replaces: CBL600
Postać fizyczna
Format: Purified
Protein G
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Przechowywanie i stabilność
Stable for 1 year at 2-8°C from date of receipt.
Komentarz do analizy
Control HeLa cells
Informacje prawne
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Minimum order quantity required to qualify. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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