Kluczowe dokumenty

Wyświetl całą dokumentację

Przejdź do

AB3000

Anti-IP3 Receptor Type II Antibody

Name: Anti-IP3 Receptor Type II Antibody
Brand: MM

Chemicon^®, from rabbit

Synonim(y):

Inositol 1,4,5-Trisphosphate Receptor

Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Informacje o tej pozycji

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ICC, IF, IHC, IP, WB

Citations:

Ten produkt nie jest już w sprzedaży. Skontaktuj się z zespołem ds. pomocy technicznejdla wsparcia

Właściwości

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, hamster, human, monkey, rat

manufacturer/tradename

Chemicon^®

technique(s)

immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

NM_002223.2

UniProt accession no.

Q14571

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITPR2(3709)

Opis

Immunogen

Synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor

Application

Anti-IP3 Receptor Type II Antibody detects level of IP3 Receptor Type II & has been published & validated for use in IC, IF, IH, IP & WB.

Research Category
Signaling

Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

Western blot: 1:50 - 1:100 (detects a 260 kDa band)

Immunofluorescence: 1:10 - 1:20

Immunoprecipitation

Immunocytochemistry: Known to give positive reactivity on AR4-2J, HL-60, COS-I, HEK-293, and RBL-2H3 cell lines.

Immunohistochemistry: Paraformaldehyde or methanol fixes are effective.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Rabbit anti-Type II Inositol 1,4,5-Trisphosphate Receptor (IP3R) is directed against a synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor. The antibody is reactive with Type II IP3R from rat, mouse, human, hamster, and monkey.

Physical form

Affinity purified versus immobilized immunogen peptide. Liquid in PBS buffer, containing 0.05% BSA, 10% glycerol, 0.005% sodium azide. Caution: Sodium azide is hazardous. MSDS available upon request.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 1

Ta pozycja	AB9074	AB9076	HPA040454
Sigma-Aldrich AB3000 Anti-IP3 Receptor Type II Antibody	Sigma-Aldrich AB9074 Anti-IP3 Receptor 2 Antibody	Sigma-Aldrich AB9076 Anti-IP3 Receptor 3 Antibody	Sigma-Aldrich HPA040454 Anti-ITPKA antibody produced in rabbit
antibody form affinity isolated antibody	antibody form serum	antibody form serum	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
UniProt accession no. Q14571	UniProt accession no. Q14571	UniProt accession no. Q14573	UniProt accession no. P23677
technique(s) immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable, immunofluorescence: suitable, immunoprecipitation (IP): suitable	technique(s) immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable	technique(s) immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable	technique(s) immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL
species reactivity mouse, hamster, human, monkey, rat	species reactivity human, mouse	species reactivity mouse, rat, human	species reactivity human

Still not finding the right product?

Wypróbuj nasze narzędzie Narzędzie selektora produktów, aby zawęzić opcje.

Klasa składowania

10 - Combustible liquids

wgk

WGK 2

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Powiązane treści

PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

Agonist-evoked inositol trisphosphate receptor (IP3R) clustering is not dependent on changes in the structure of the endoplasmic reticulum.

Mark Chalmers et al.

The Biochemical journal, 394(Pt 1), 57-66 (2005-11-09)

The size and number of IP3R (inositol 1,4,5-trisphosphate receptor) clusters located on the surface of the ER (endoplasmic reticulum) is hypothesized to regulate the propagation of Ca2+ waves in cells, but the mechanisms by which the receptors cluster are not

Short-term high-fat diet feeding of mice suppresses catecholamine-stimulated Ca2+ signalling in hepatocytes and intact liver.

Robert P Brumer et al.

The Journal of physiology, 601(8), 1383-1405 (2023-03-04)

Excess consumption of carbohydrates, fat and calories leads to non-alcoholic fatty liver disease (NAFLD) and hepatic insulin resistance; these are major factors in the pathogenesis of type II diabetes. Hormones and catecholamines acting through G-protein coupled receptors (GPCRs) linked to

PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth.

Shafi Kuchay et al.

Nature, 546(7659), 554-558 (2017-06-15)

In response to environmental cues that promote IP3 (inositol 1,4,5-trisphosphate) generation, IP3 receptors (IP3Rs) located on the endoplasmic reticulum allow the 'quasisynaptical' feeding of calcium to the mitochondria to promote oxidative phosphorylation. However, persistent Ca2+ release results in mitochondrial Ca2+