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AB2031

Sigma-Aldrich

Anti-Collagen Type II Antibody

Chemicon®, from rabbit

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

rabbit

forma przeciwciała

affinity purified immunoglobulin

rodzaj przeciwciała

primary antibodies

klon

polyclonal

reaktywność gatunkowa

bovine, mouse

producent / nazwa handlowa

Chemicon®

metody

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
radioimmunoassay: suitable

numer dostępu UniProt

Warunki transportu

dry ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

mouse ... Col2A1(12824)

Specyficzność

Antibody shows by RIA cross reactivity with mouse collagen types I, III, IV of less than 0.1% at a dilution of 1:100. The antibody also demonstrates a reactivity with mouse fibronectin of less than 0.1% by RIA at dilution of 1:100. There is also cross reactivity with bovine collagen type II by ELISA

Immunogen

Collagen Type II extracted and purified from mouse fetal cartilage.

Zastosowanie

Anti-Collagen Type II Antibody is an antibody against Collagen Type II for use in ELISA, IF, RIA, IH.
Immunohistochemistry: 1:40-1:80 dilution for immunofluorescent staining of fresh frozen mouse articular tissue. Acetone or methyl-carnoy fixation is also reactive.

Radioimmunoassay

ELISA

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Postać fizyczna

Format: Purified
Protein G affinity purified IgG fraction at 1.0 mg/mL in 0.01M phosphate, 0.09M NaCl, pH 7.2 with no preservatives.

Przechowywanie i stabilność

Maintain frozen at -20°C for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Yucheng Lin et al.
Arthritis research & therapy, 26(1), 111-111 (2024-05-30)
Due to the unclear pathogenesis of osteoarthritis (OA), effective treatment for this ailment is presently unavailable. Accumulating evidence points to chondrocyte senescence as a key driver in OA development. This study aims to identify OA-specific microRNAs (miRNAs) targeting chondrocyte senescence
Bone mesenchymal stem cell-derived extracellular vesicles promote the repair of intervertebral disc degeneration by transferring microRNA-199a.
Wen, et al.
Cell Cycle, 20, 256-270 (2022)
Issaka Yougbaré et al.
The Journal of clinical investigation, 125(4), 1545-1556 (2015-03-17)
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a life-threatening disease in which intracranial hemorrhage (ICH) is the major risk. Although thrombocytopenia, which is caused by maternal antibodies against β3 integrin and occasionally by maternal antibodies against other platelet antigens, such
Ivana Gadjanski et al.
Tissue engineering. Part A, 19(19-20), 2188-2200 (2013-05-09)
Formation of tissue-engineered cartilage is greatly enhanced by mechanical stimulation. However, direct mechanical stimulation is not always a suitable method, and the utilization of mechanisms underlying mechanotransduction might allow for a highly effective and less aggressive alternate means of stimulation.

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