324904

Epiregulin, Mouse, Recombinant

Epiregulin, Mouse, Recombinant is expressed in E. coli with an N-terminal methionine. Inhibits epithelial tumor growth and stimulates the growth of fibroblasts and other cell types.

• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• rekombinowane: expressed in E. coli
• Poziom jakości: 100
• Próba: ≥97% (SDS-PAGE)
• Postać: liquid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• zanieczyszczenia: <1.0 EU/μg protein Endotoxin
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Opis ogólny

Recombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.

Działania biochem./fizjol.

ED₅₀ = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

Lyophilized from 0.2 µm sterile-filtered PBS, BSA.

Rekonstytucja

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 10 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

Inne uwagi

Shirakata, Y., et al. 2000. J. Biol. Chem.275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem.273, 10496.
Das, S.K., et al. 1997. Dev. Biol.190, 178.
Komurasaki, T., et al. 1997. Oncogene15, 2841.
Toyoda, H., et al. 1995. J. Biol. Chem.270, 7495.
Toyoda, H., et al. 1995. FEBS Lett.377, 403.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 13 - Non Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable