17-218
Ras Activation Assay Kit
Synonim(y):
Ras Activity Assay
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1 KIT
4210,00 zł
4210,00 zł
Przewidywany termin wysyłki28 stycznia 2025Szczegóły
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1 KIT
4210,00 zł
About This Item
Kod UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84
4210,00 zł
Przewidywany termin wysyłki28 stycznia 2025Szczegóły
Polecane produkty
producent / nazwa handlowa
Upstate®
Poziom jakości
metody
activity assay: suitable
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
dry ice
informacje o genach
human ... MRAS(22808)
Opis ogólny
Muscle RAS oncogene homolog (MRAS) plays a key role in cardiovascular diseases. The MRAS gene codes for a member of the ras superfamily of GTP-binding proteins. MRAS is found in all tissues, particularly in the cardiovascular system. It is involved in signal transduction, including cell growth and differentiation.[1]
Opakowanie
Kit capacity: 30 assays
Komponenty
Ras Assay Reagent (Raf-1 RBD, agarose) (Cat.# 14-278)
Anti-Ras, clone RAS10 (Cat.# 05-516)
100X GTPγS, 10mM (Cat.# 20-176)
100X GDP, 100mM (Cat.# 20-177)
Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)
Anti-Ras, clone RAS10 (Cat.# 05-516)
100X GTPγS, 10mM (Cat.# 20-176)
100X GDP, 100mM (Cat.# 20-177)
Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)
Jakość
This kit precipitated Ras-GTP from HeLa cell lysates that had been loaded with GTPγS. The precipitated Ras-GTP was detected by western immunoblot using 1μg/ml anti-Ras, clone RAS10
Powiązanie
Replaces: SGT435
Informacje prawne
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
Kod klasy składowania
10 - Combustible liquids
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
AnhCo Nguyen et al.
Molecular and cellular biology, 22(9), 3035-3045 (2002-04-10)
While scaffold proteins are thought to be key components of signaling pathways, their exact function is unknown. By preassembling multiple components of signaling cascades, scaffolds are predicted to influence the efficiency and/or specificity of signaling events. Here we analyze a
Shin-Ichiro Miura et al.
Atherosclerosis, 175(2), 235-243 (2004-07-21)
Since we recently demonstrated that high-density lipoprotein induced human coronary artery endothelial cell (HCEC) tube formation through Ras/Raf/ERK (extracellular-signal-regulated kinase) activation [Arterioscler. Thromb. Vasc. Biol. 23 (2003) 802], it is possible that lipid-lowering agents such as statins, which reduce the
Richard J Calvert et al.
Analytical biochemistry, 343(2), 283-292 (2005-07-16)
Accurate measurement of activity of wild-type K-ras protein is important due to its tumor suppressor action in tissues such as lung. A published method by Taylor and co-workers uses plasmid-containing Escherichia coli cells to produce a glutathione-S-transferase/raf-1 ras binding domain
X Shen et al.
The Biochemical journal, 352 Pt 3, 913-919 (2000-12-06)
Interleukin 1beta (IL-1beta) suppresses the IL-6-dependent induction of type II acute-phase response genes, but the underlying mechanism for this suppression remains uncertain. Here we report that treatment of human hepatocullular carcinoma HepG2 cells with IL-1beta inhibited the IL-6-dependent binding of
J Kim et al.
The Journal of biological chemistry, 276(22), 19102-19110 (2001-03-23)
AMP-activated protein kinase (AMPK) is tightly regulated by the cellular AMP:ATP ratio and plays a central role in the regulation of energy homeostasis. Previously, AMPK was reported to phosphorylate serine 621 of Raf-1 in vitro. In the present study, we
Produkty
Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.
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