N-terminal 6His-tagged, recombinant, full length PKG1α.
Product Source: PKG1α, expressed by baculovirus in Sf21 cells.
Zastosowanie
Research Category Inflammation & Immunology
Działania biochem./fizjol.
Protein Target: PKG1α
Target Sub-Family: AGC
Jakość
routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
Postać fizyczna
Ni2+/NTA-agarose
Przechowywanie i stabilność
6 months at -70°C from date of shipment
Inne uwagi
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Informacje prawne
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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It is currently accepted that cGMP-dependent protein kinase (PKG) inhibits platelet activation. Here, we show that PKG plays an important stimulatory role in platelet activation. Expression of recombinant PKG in a reconstituted cell model enhanced von Willebrand factor (vWF)-induced activation
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