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810241P

Avanti

TopFluor™ TMR PE

Avanti Research™ - A Croda Brand 810241P, powder

Synonim(y):

1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphoethanolamine

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About This Item

Wzór empiryczny (zapis Hilla):
C50H76 BF2N4 O10P
Numer CAS:
2260795-41-1
Masa cząsteczkowa:
972.94
Kod UNSPSC:
12352211
NACRES:
NA.25

Próba

>99% (TLC)

Postać

powder

opakowanie

pkg of 1 × 1 mg (810241P-1mg)

producent / nazwa handlowa

Avanti Research™ - A Croda Brand 810241P

Warunki transportu

dry ice

temp. przechowywania

−20°C

Opis ogólny

Phosphoethanolamine contains a phosphate group linked with the second carbon of ethanolamine.

Działania biochem./fizjol.

Phosphoethanolamine (PEA) is a precursor to phosphatidylethanolamine and phosphatidylcholine, involved in the biosynthesis of cell membrane. In human body, PEA is a product of degradation of sphingosine phosphate and endocannabinoid anandamide. PEA has potential cytotoxic properties and is known to induce the caspase-independent cell death. PEA is capable of inhibiting tumor growth in vitro and in vivo in mouse models.

Opakowanie

5 mL Amber Glass Screw Cap Vial (810241P-1mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Kod klasy składowania

11 - Combustible Solids

Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Lisley I Mambelli et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 103, 18-28 (2018-04-11)
Phosphoethanolamine (PEA) is a fundamental precursor during the biosynthesis of cell membranes phospholipids. In the past few years, it has been described as a potential antitumor agent. In previous studies, we demonstrated that PEA showed antitumor properties in vitro and
Noam Pondé et al.
Ecancermedicalscience, 10, 681-681 (2016-12-03)
The use of unproven forms of therapy in cancer treatment is very common. In Brazil, the distribution by researchers to patients of an investigational agent called phophoethanolamine (PHOS) has led to a widely publicized scientific scandal. PHOS is a precursor
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely

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