SMAD4
SMAD family member 4
Synonimy:
DPC4, JIP, MADH4, MYHRS
Gatunek:
Human SMAD4 (4089), Mouse Smad4 (17128), Rat Smad4 (50554), dog SMAD4 (476196), domestic cat SMAD4 (101093650), Zebrafish smad4 (30640), domestic guinea pig Smad4 (100717853), naked mole-rat Smad4 (101703764), sheep SMAD4 (443171), cow SMAD4 (540248) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(4089) Summary: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]
- Mouse(17128) SMAD family member 4
- Rat(50554) SMAD family member 4
- dog(476196) SMAD family member 4
- domestic cat(101093650) SMAD family member 4
- Zebrafish(30640) MAD homolog 4 (Drosophila)
- domestic guinea pig(100717853) SMAD family member 4
- naked mole-rat(101703764) SMAD family member 4
- sheep(443171) SMAD family member 4
- cow(540248) SMAD family member 4
- Horse(100033846) SMAD family member 4
- Goat(100861019) SMAD family member 4
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ELISA
Numer produktu
Opis
Gatunek
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SMAD4 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM277, purified immunoglobulin,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-SMAD4 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, sheep
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-SMAD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ChIP
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
[Zatwierdzone przez KO] Przeciwciało anty-Smad4, klon 1H7D3, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
ChIP
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
ANTI-SMAD4 antibody produced in mouse, clone 3D7, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Cell Lines
Proteins
Numer produktu
Opis
Gatunek
SMAD4, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human