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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Synonimy:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-SCN5A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, guinea pig, horse, human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało przeciw kanałowi sodowemu Nav1.5, ból, Chemicon®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Flecainide acetate salt, ,
Gatunek
human
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Flecainide acetate, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Octan flekainidu, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Flecainide acetate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
Lamotrigine, ≥98%, powder,
Gatunek
rat, human
Carbamazepine, powder,
Gatunek
rat, human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SCN5A,
Gatunek
human