F-017

(±)-Flecainide solution

Name: (±)-Flecainide solution
Brand: CERILLIAN
Price: 309 PLN

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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1 ML

309,00 zł

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₁₇H₂₀F₆N₂O₃

Numer CAS:

54143-55-4

Masa cząsteczkowa:

414.34

NACRES:

NA.24

PubChem Substance ID:

329799633

UNSPSC Code:

41116107

EC Number:

200-659-6

MDL number:

MFCD00864713

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Nazwa produktu

(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

InChI key

DJBNUMBKLMJRSA-UHFFFAOYSA-N

InChI

1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)

SMILES string

O=C(NCC1CCCCN1)C2=CC(OCC(F)(F)F)=CC=C2OCC(F)(F)F

grade

certified reference material

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

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Ta pozycja	T-910	F-903	P-121
Supelco F-017 (±)-Flecainide solution	Supelco T-910 Triazolam solution	Supelco F-903 Fluphenazine dihydrochloride solution	Supelco P-121 Prednisolone solution
technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable
form liquid	form liquid	form liquid	form liquid
format single component solution	format single component solution	format single component solution	format single component solution
Quality Level 300	Quality Level 300	Quality Level 300	Quality Level 300
grade certified reference material	grade certified reference material	grade certified reference material	grade certified reference material
storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C

General description

Flecainide, marketed under trade names such as Almarytm, Apocard, Ecrinal^®, and Flécaine, is a class Ic antiarrhythmic drug used to prevent and treat a variety of cardiac arrhythmias. This Certified Spiking Solution^® is suitable for use as a starting material in the preparation of calibrators, controls, or linearity standards in flecainide therapeutic drug monitoring methods by LC/MS or LC that ensure patients remain within the drug′s narrow therapeutic range.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Ecrinal is a registered trademark of Laboratoires Asepta Corporation Monaco

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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related product

Numer produktu

Opis

Cennik

F-098

Flecainide-D₄ solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant^®

pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Klasa składowania

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Comparison of the intrinsic vasorelaxant and inotropic effects of the antiarrhythmic agents vernakalant and flecainide in human isolated vascular and cardiac tissues.

Joseph J Lynch et al.

Journal of cardiovascular pharmacology, 61(3), 226-232 (2012-11-29)

This study explored the intrinsic vasorelaxant and inotropic effects of the mixed potassium and sodium channel blocker atrial antiarrhythmic vernakalant and the class IC antiarrhythmic agent flecainide in human isolated subcutaneous resistance artery and in ventricular trabecular muscle preparations. At

Antiarrhythmic drug treatment after cardioversion of atrial fibrillation.

Marcelle D Smit et al.

Lancet (London, England), 380(9852), 1467-1467 (2012-10-30)

ECG diagnosis: flecainide toxicity.

Joel T Levis

The Permanente journal, 16(4), 53-53 (2012-12-20)

A case of near-fatal flecainide overdose in a neonate successfully treated with sodium bicarbonate.

David H Jang et al.

The Journal of emergency medicine, 44(4), 781-783 (2012-09-18)

Flecainide is a class IC antidysrhythmic primarily indicated for ventricular dysrhythmias and supraventricular tachycardia (SVT). Class IC antidysrhythmic overdose has a reported mortality of 22%, and death results from dysrhythmias and cardiovascular collapse. We report a near-fatal flecainide overdose in

Brugada pattern masquerading as ST-segment elevation myocardial infarction in flecainide toxicity.

Lovely Chhabra et al.

Indian heart journal, 64(4), 404-407 (2012-08-30)

Flecainide (a class 1c antiarrhythmic) produces a dose-dependent decrease in intracardiac conduction. Its well known common electrocardiographic effects are prolongation of PR and QT intervals and the QRS complex duration. We report a case of flecainide toxicity in an elderly

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