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RPS6KB1

ribosomal protein S6 kinase, 70kDa, polypeptide 1

Synonimy:
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6198) Summary: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
  • Mouse(72508) ribosomal protein S6 kinase, polypeptide 1
  • Rat(83840) ribosomal protein S6 kinase, polypeptide 1
  • cow(404181) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • sheep(101107371) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • chicken(417637) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Domestic Rabbit(100009260) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • domestic cat(101092561) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Horse(100057481) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • dog(480580) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • domestic guinea pig(100727216) ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • naked mole-rat(101724077) ribosomal protein S6 kinase, 70kDa, polypeptide 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-RPS6KB1, (C-terminal) antibody produced in mouse, clone 1E10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

proximity ligation assay

western blot
Przeciwciało anty-p70 S6 Kinase 1, klon 1S7Y4, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
Anty-fosfo-p70kinaza S6 (pThr389/412), affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Przeciwciało anty-Phospho-P70S6K1-T389produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Przeciwciało anty-P70S6K produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
PF-4708671, ≥98% (HPLC),
Gatunek
human, mouse, rat

Proteins

Numer produktu
Opis
Gatunek
p70S6K active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Gatunek
human
p70S6K, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
Białko kinazy p70 S6, aktywne, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase, for use in Kinase Assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human RPS6KB1,
Gatunek
human