PTK2B
protein tyrosine kinase 2 beta
Synonimy:
CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK
Gatunek:
Human PTK2B (2185), Mouse Ptk2b (19229), Rat Ptk2b (50646), domestic cat PTK2B (101091691), dog PTK2B (486102), chicken PTK2B (421998), domestic guinea pig Ptk2b (100734027), naked mole-rat Ptk2b (101714384), cow PTK2B (541008), sheep PTK2B (101106906) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2185) Summary: This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19229) PTK2 protein tyrosine kinase 2 beta
- Rat(50646) protein tyrosine kinase 2 beta
- domestic cat(101091691) PTK2B protein tyrosine kinase 2 beta
- dog(486102) PTK2B protein tyrosine kinase 2 beta
- chicken(421998) PTK2B protein tyrosine kinase 2 beta
- domestic guinea pig(100734027) protein tyrosine kinase 2 beta
- naked mole-rat(101714384) protein tyrosine kinase 2 beta
- cow(541008) PTK2B protein tyrosine kinase 2 beta
- sheep(101106906) PTK2B protein tyrosine kinase 2 beta
- Domestic Rabbit(100342358) PTK2B protein tyrosine kinase 2 beta
- Horse(100054547) PTK2B protein tyrosine kinase 2 beta
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Numer produktu
Opis
Gatunek
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-PYK2 (pTyr881) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-Pyk2/CAKβ/FAK2 (Tyr402) Antibody, Upstate®, from rabbit,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunocytochemistry
western blot
western blot
Anti-Phospho-PTK2B-Y402 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anti-PYK2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
immunohistochemistry
Anti-PTK2B (Ab-402) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Numer produktu
Opis
Gatunek
Pyk2 Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Pyk2. For use in Kinase Assays.,
Gatunek
human