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Merck

P2RY12

purinergic receptor P2Y, G-protein coupled, 12

Synonimy:
ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(64805) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(70839) purinergic receptor P2Y, G-protein coupled 12
  • Rat(64803) purinergic receptor P2Y, G-protein coupled, 12
  • dog(442958) purinergic receptor P2Y, G-protein coupled, 12
  • cow(408007) purinergic receptor P2Y, G-protein coupled, 12
  • sheep(101117897) purinergic receptor P2Y, G-protein coupled, 12
  • naked mole-rat(101701294) purinergic receptor P2Y, G-protein coupled, 12
  • domestic cat(101094044) purinergic receptor P2Y, G-protein coupled, 12
  • domestic guinea pig(100720551) purinergic receptor P2Y, G-protein coupled, 12

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Ticagrelor, ≥98% (HPLC),
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Ticlopidine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Ticlopidine hydrochloride, analytical standard, for drug analysis,
Gatunek
human
Prasugrel for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Ticlopidine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Clopidogrel Bisulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-P2RY12 Antibody, clone 2C12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
bovine, human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-P2RY12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-P2RY12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Receptor anty-P2Y12, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
Anti-Purinergic Receptor P2Y12 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse P2ry12,
Gatunek
mouse
MISSION® esiRNA, targeting human P2RY12,
Gatunek
human