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Merck

KCNQ1

potassium voltage-gated channel, KQT-like subfamily, member 1

Synonimy:
ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3784) Summary: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(16535) potassium voltage-gated channel, subfamily Q, member 1
  • Rat(84020) potassium voltage-gated channel, KQT-like subfamily, member 1
  • chicken(423090) potassium voltage-gated channel, KQT-like subfamily, member 1
  • naked mole-rat(101725681) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic guinea pig(100379230) potassium voltage-gated channel, subfamily Q, member 1
  • sheep(101119596) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic cat(101092644) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Horse(100034129) potassium voltage-gated channel, KQT-like subfamily, member 1
  • cow(784876) potassium voltage-gated channel, KQT-like subfamily, member 1
  • dog(483669) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Zebrafish(557498) potassium voltage-gated channel, KQT-like subfamily, member 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-KCNQ1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-Kcnq1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-KCNQ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-KCNQ1, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Anti-Potassium Channel KvLQT1 Antibody, CT, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Retigabine, ≥98% (HPLC),
Gatunek
human
Retigabine, analytical standard,
Gatunek
human
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
Gatunek
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Gatunek
human
Guanidine hydrochloride, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human KCNQ1,
Gatunek
human
MISSION® esiRNA, targeting mouse Kcnq1,
Gatunek
mouse