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Merck

CYP2C9

cytochrome P450, family 2, subfamily C, polypeptide 9

Synonimy:
CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
Gatunek:
Human CYP2C9 (1559)
Identyfikator UniProtKB:
P11712, P11713, Q16756, Q16872, Q5VX92
Identyfikator genu:
  • Human(1559) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
HPA015066
Anti-CYP2C9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
SAB1305083
MONOCLONAL ANTI-CYP2C9 (N-TERMINAL) antibody produced in mouse, crude ascites, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
SAB6012093
Anti Cytochrome P450 2C9 Antibody, clone 23GB5885, Rabbit Monoclonal, clone 23GB5885, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
T5535
Thiabendazole, BioReagent, suitable for plant cell culture, powder,
Gatunek
human
T8904
Thiabendazole, ≥99%, powder,
Gatunek
human
M1390
3,3′-Methylene-bis(4-hydroxycoumarin), ,
Gatunek
human
B5774
Benzbromarone, analytical standard,
Gatunek
human
S0758
Sulfaphenazole, ≥98%,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
H4667
Cytochrom P450 2C9*2 (R144C), ludzki, recombinant, expressed in E. coli,
Gatunek
human
MTOXCE2C9
CypExpress™ 2C9 Cytochrom P450 ludzki, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU111841
MISSION® esiRNA, targeting human CYP2C9,
Gatunek
human

Small Molecule - Substrate

Numer produktu
Opis
Gatunek
T0891
Tolbutamide, analytical standard,
Gatunek
human, mouse